Results 31 to 40 of about 270,230 (255)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Exploration of Candidate Genes for Fiber Length in Gossypium mustelinum Based on BSA-seq
Nantong Daxue xuebao. Ziran kexue ban, 2021 Fiber length is one of the important characteristics of cotton fiber quality. It is of great significance to explore fiber length genes for breeding of cotton varieties with elite fiber quality. In the first phase of the study, 15 quantitative trait loci(
CHEN Qi +8 more
doaj +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Tạp chí Khoa học và Công nghệLotus silk is a natural fiber with high economic value; however, current production remains largely manual, resulting in low productivity and limited scalability. This study experimentally investigates the length of lotus fibers drawn under the influence
Vinh-Phuc Mai +5 more
doaj +1 more source
Frontiers in Plant Science, 2020 Accurate phenotype prediction of quantitative traits is paramount to enhanced plant research and breeding. Here, we report the accurate prediction of cotton fiber length, a typical quantitative trait, using 474 cotton (Gossypium ssp.) fiber length (GFL ...
Yun-Hua Liu +7 more
doaj +1 more source
Journal of Natural Fibers, 2022 New Zealand is the third-largest producer of wool in the world and accounts for approximately 9.3% of world production (approx. 140,000 tonnes greasy annually).
Peter Baxter, Jeremy Wear
doaj +1 more source
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Frontiers in NeurologyObjectiveTo investigate the application of musculoskeletal ultrasound in the quantitative assessment of lower leg muscles and its value in stratifying rehabilitation outcomes in patients with stroke.MethodsA single-center retrospective study was ...
Chengrui Ma +3 more
doaj +1 more source