Results 51 to 60 of about 478,180 (342)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

3D printed near-infrared high-numerical aperture achromatic metalens

iScience
Summary: Traditional optical Fresnel microlenses have limitations such as large size, limited optical quality for imaging, and low focusing efficiency in achromatic lenses with high NA.
Heming Wei, Wenchen Hu, Jingtian Hu, Guoqiang He, Fufei Pang, Sridhar Krishnaswamy, Jan Nedoma, Carlos Marques   +7 more
doaj   +1 more source

Scalable fiber integrated source for higher-dimensional path-entangled photonic quNits

, 2012
Integrated photonic circuits offer the possibility for complex quantum optical experiments in higher-dimensional photonic systems. However, the advantages of integration and scalability can only be fully utilized with the availability of a source for ...
Fickler, Robert, Lapkiewicz, Radek, Polster, Robert, Ramelow, Sven, Schaeff, Christoph, Zeilinger, Anton   +5 more
core   +1 more source

Hybrid Fiber Optic Sensor Systems in Structural Health Monitoring in Aircraft Structures

Materials, 2020
‘Smart’ structural health monitoring of composite materials with optical fiber sensors is becoming more and more important, especially in the aviation industry.
Karolina Bednarska, P. Sobotka, T. Wolinski, Oliwia Zakręcka, Wiktor Pomianek, Agnieszka Nocoń, P. Lesiak   +6 more
semanticscholar   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Solitary waves in nonlocal NLS with dispersion averaged saturated nonlinearities [PDF]

, 2017
A nonlinear Schr\"odinger equation (NLS) with dispersion averaged nonlinearity of saturated type is considered. Such a nonlocal NLS is of integro-differential type and it arises naturally in modeling fiber-optics communication systems with periodically ...
Hundertmark, Dirk, Lee, Young-Ran, Ried, Tobias, Zharnitsky, Vadim   +3 more
core   +3 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Laser-actuated mechanical device [PDF]

, 1974
Actuator is portable and can be used in high-temperature (over 500 C) environments by incorporating tungsten metal film and quartz window. Actuator can be triggered when it is not directly in laser beam path by utilizing fiber optics.
Murphy, A. J., Yang, L. C.
core   +1 more source

Multi-component optical solitary waves

, 2000
We discuss several novel types of multi-component (temporal and spatial) envelope solitary waves that appear in fiber and waveguide nonlinear optics. In particular, we describe multi-channel solitary waves in bit-parallel-wavelength fiber transmission ...
Agranovich, Agrawal, Andrey A Sukhorukov, Assanto, Baldi, Balslev Clausen, Balslev Clausen, Bergman, Boardman, Boardman, Buryak, Buryak, Buryak, Carl Balslev Clausen, Chen, Dmitriev, Elena A Ostrovskaya, Fejer, Gellermann, Gredeskul, Hasegawa, Hasegawa, Hasegawa, Hopkins, Kivshar, Kivshar, Kivshar, Kivshar, Koynov, Malomed, Menyuk, Mitchell, Mitchell, Ole Bang, Pelinovsky, Peter L Christiansen, Pfister, Schechtman, Solomon M Saltiel, Steblina, Stegeman, Sulem, Tristram J Alexander, Yeh, Yeh, Yuri S Kivshar, Zhu, Zhu, Zhu   +48 more
core   +2 more sources

Chemo-optical microsensing systems [PDF]

, 1991
Chemo-optical microsensing systems, whether based on fiber optics or integrated optics, show promising prospects. The physical principles underlying chemo-optical waveguide sensors are discussed with the accent on linear evanescent field sensors.
Lambeck, Paul V.
core   +3 more sources