Results 71 to 80 of about 5,056,746 (334)
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Effect of Chemically Modified Banana Fibers on the Mechanical Properties of Poly-Dimethyl-Siloxane-Based Composites [PDF]
, 2019 The study presents the mechanical properties of polymer-based composites reinforced with chemically modified banana fibers, by alkalization in different concentrations of sodium hydroxide (NaOH).
ABADE-ABUGRE, Miriam +9 more
core
Study of Scintillator Strip with Wavelength Shifting Fiber and Silicon Photomultiplier
, 2007 The performance of the $200\times2.5\times1$ cm$^3$ plastic scintillator strip with wavelength shifting fiber read-out by two novel photodetectors called Silicon PhotoMultipliers (SiPMs) is discussed.
Adamson +16 more
core +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
On the normality of the null-fiber of the moment map for $\theta$- and tori representations
, 2017 Let (G, V) be a representation with either G a torus or (G, V) a locally free stable $\theta$-representation. We study the fiber at 0 of the associated moment map, which is a commuting variety in the latter case.
Bulois, Michael
core +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
, 1955 Tables cover acreage, yield, production, stocks, prices, and related data. Includes tables on grains, food and fiber crops, soybeans and cowpeas, hay, and field seeds.published or submitted for publicationnot peer ...
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
AgricultureBreeding programs rely on genotype-by-environment interaction (GEI) to recommend cultivars for specific locations. GEI describes how different genotypes perform under varying environmental conditions.
Matheus Massariol Suela +7 more
doaj +1 more source
Journal of Natural Fibers, 2022 Correlation and path coefficient analysis aid in developing breeding strategies aimed at increasing yield traits through selection by providing a better understanding of the relationship.
Md Al-Mamun +7 more
doaj +1 more source