Results 51 to 60 of about 1,459,866 (304)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Publisher Correction: Direct electronetting of high-performance membranes based on self-assembled 2D nanoarchitectured networks

Nature Communications, 2020
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Shichao Zhang, Hui Liu, Ning Tang, Jianlong Ge, Jianyong Yu, Bin Ding   +5 more
doaj   +1 more source

Preparation of SnIn4S8/TiO2 Nanotube Photoanode and Its Photocathodic Protection for Q235 Carbon Steel Under Visible Light

Nanoscale Research Letters, 2021
TiO2 is an attractive semiconductor suitable for photocathodic protection, but its weak absorption of visible light and low quantum yield limit its usage.
Hong Li, Weizhe Song, Xingqiang Cui, Yanhui Li, Baorong Hou, Lianjun Cheng, Pengfei Zhang   +6 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Modelling Cotton Fiber Doffing From Saw Teeth Based On A Mathematical Model [PDF]

E3S Web of Conferences
In recent years, there have been many researches devoted to the theoretical foundations of the sawing process. However, among them, there are none devoted to the study of the process of extracting the fiber separated from the seed from the saw teeth ...
Yuldashev Khasanboy, Sharipov Khayrullo, Najmitdinov Shukhrat, Inamova Maftuna, Ruzimatov Sanjar   +4 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Characterizing octagonal and rectangular fibers for MAROON-X

, 2016
We report on the scrambling performance and focal-ratio-degradation (FRD) of various octagonal and rectangular fibers considered for MAROON-X. Our measurements demonstrate the detrimental effect of thin claddings on the FRD of octagonal and rectangular ...
Bean, Jacob L., Miller, Katrina R., Seifahrt, Andreas, Stürmer, Julian, Sutherland, Adam P.   +4 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Glass fiber addition strengthens low-density ablative compositions [PDF]

, 1974
Approximately 15% of E-glass fibers was added to compositions under test and greatly improved char stability. Use of these fibers also reduced thermal strains which, in turn, minimized char shrinkage and associated cracks, subsurface voids, and disbonds.
Chandler, H. H.
core   +1 more source

Experimental stress-strain analysis of tapered silica optical fibers with nanofiber waist

, 2014
We experimentally determine tensile force-elongation diagrams of tapered optical fibers with a nanofiber waist. The tapered optical fibers are produced from standard silica optical fibers using a heat and pull process. Both, the force-elongation data and
Hoinkes, Thomas, Holleis, Sigrid, Rauschenbeutel, Arno, Schneeweiss, Philipp, Wuttke, Christian   +4 more
core   +1 more source