Results 51 to 60 of about 1,500 (185)

Fragment‐Based Design of Targeted Covalent Inhibitors: The Scope and Limitation of Linking Approaches

ChemMedChem, Volume 21, Issue 10, 27 May 2026.
This paper by Kollár et al. reports a covalent fragment linking study against the SARS‐CoV‐2 main protease (3CLPro). Beginning with inactive fragment hits, the application of rational linker design enabled the generation of reversible covalent inhibitors exhibiting low micromolar potency. The study details some general limitations and best practices of
Levente Kollár, Levente M. Mihalovits, Dávid Bajusz, Damijan Knez, József Simon, Blake H. Balcomb, Daren Fearon, Stanislav Gobec, György M. Keserű   +8 more
wiley   +1 more source

Elementary sequences, sub-Fibonacci sequences

Discrete Applied Mathematics, 1993
A nondecreasing integer sequence \(x_ 1,x_ 2,\dots,x_ k\) with \(x_ 1=x_ 2=1\) and \(n \geq 2\) is said to be elementary if for all \(k \leq n\) \((x_ k>1 \Rightarrow x_ k=x_ i+x_ j\) for some \(i \neq j)\) and sub- Fibonacci if for all \(k \in \{3,\dots,n\}\) \((x_ k \leq x_{k-1}+x_{k- 2})\).
Peter C. Fishburn, Fred S. Roberts
openaire   +1 more source

Generalized Fibonacci sequences in groupoids [PDF]

Advances in Difference Equations, 2013
Abstract In this paper, we introduce the notion of generalized Fibonacci sequences over a groupoid and discuss it in particular for the case where the groupoid contains idempotents and pre-idempotents. Using the notion of Smarandache-type P-algebra, we obtain several relations on groupoids which are derived from generalized Fibonacci ...
Kim, Hee, Neggers, J, So, Keum
openaire   +1 more source

Non‐Subtractive Arterial Spin Labeling‐Based (NSASL) Renal Magnetic Resonance Angiography (MRA): Development and Clinical Feasibility Evaluation

Journal of Magnetic Resonance Imaging, Volume 63, Issue 5, Page 1435-1447, May 2026.
ABSTRACT Background Non‐contrast renal MR angiography (MRA) is valuable for patients who cannot receive contrast agents or when avoiding radiation is desired. However, the conventional inflow inversion recovery (IFIR) method is limited by incomplete background suppression, venous contamination, and motion sensitivity.
Yulin Wang, Ye Yuan, Kun Yan, Jichang Zhang, Jie Zeng, Shengyang Niu, Shiying Ke, Chendie Yao, Bin Chen, Qi Dai, Liping Guo, Jianjun Zheng, Thomas Meersmann, Chengbo Wang   +13 more
wiley   +1 more source

Diophantine equations with Lucas and Fibonacci number coefficients [PDF]

Notes on Number Theory and Discrete Mathematics
Fibonacci and Lucas numbers are special number sequences that have been the subject of many studies throughout history due to the relations they provide.
Cemil Karaçam, Alper Vural, Bilal Aytepe, Ferhat Yıldız   +3 more
doaj   +1 more source

Pole‐To‐Pole 3D Radial Trajectory Designs Improve Image Quality and Quantitative Parametric Mapping in the Brain and Heart

Magnetic Resonance in Medicine, Volume 95, Issue 5, Page 2627-2643, May 2026.
ABSTRACT Purpose To design 3D radial spiral phyllotaxis trajectories aimed at removing phase inconsistencies, improving image quality, and enhancing parametric mapping accuracy by acquiring nearly opposing spokes starting from both hemispheres in 3D radial k‐space. Methods Two 3D radial trajectories, pole‐to‐pole and continuous spiral phyllotaxis, were
Eva S. Peper, Grzegorz Bauman, Matteo Tagliabue, Berk C. Açikgöz, Nils M. J. Plähn, Adèle L. C. Mackowiak, Yasaman Safarkhanlo, Joseph G. Woods, Davide Piccini, Li Feng, Christopher W. Roy, Oliver Bieri, Jessica A. M. Bastiaansen   +12 more
wiley   +1 more source

On Doubled and Quadrupled Fibonacci Type Sequences

Annales Mathematicae Silesianae
In this paper we study a family of doubled and quadrupled Fibonacci type sequences obtained by distance generalization of Fibonacci sequence. In particular we obtain doubled Fibonacci sequence, doubled and quadrupled Padovan sequence and quadrupled ...
Yilmaz Nur Şeyma, Włoch Andrzej, Özkan Engin, Strzałka Dominik   +3 more
doaj   +1 more source

FIBONACCI TILINGS IN FASHION DESIGN [PDF]

Annals of the University of Oradea: Fascicle of Textiles, Leatherwork, 2016
The Fibonacci sequence is a symbol of beauty and harmony and by this reason geometrical objects in its proportions are used in the design. There are some versions of Fibonacci series tiling, which are constructed with equilateral geometrical figures ...
KAZLACHEVA Zlatina
doaj  

Mind the Gap: Linking Refactorings and Code Smells in Elixir

Journal of Software: Evolution and Process, Volume 38, Issue 5, May 2026.
ABSTRACT Elixir is a functional programming language increasingly used in the industry to develop scalable and fault‐tolerant concurrent systems more easily and with fewer computational resources. In previous studies, we cataloged 35 code smells and 82 refactorings tailored for this language, validating them with over 300 experienced developers ...
Lucas Vegi, Marco Túlio Valente
wiley   +1 more source

What does a modified-Fibonacci dose-escalation actually correspond to?

BMC Medical Research Methodology, 2012
Background In most phase I oncology trials, it is often stated that the dose increments follow a “modified-Fibonacci sequence”. This term, however, is vague.
Penel Nicolas, Kramar Andrew
doaj   +1 more source