Results 41 to 50 of about 5,732 (184)
Single‐use bioreactors (SUBs) have become crucial in bioprocessing, offering reduced contamination risks and efficient biomolecule synthesis. Research highlights their ability to achieve results comparable to conventional systems, particularly through optimized hydrodynamic conditions and wave mechanisms, making SUBs a reliable and adaptable solution ...
Debashis Dutta +3 more
wiley +1 more source
Em condições de casa de vegetação do Centro Nacional de Pesquisa do algodão (Embrapa/CNPA), estudaram-se os efeitos de doses crescentes de lodo de esgoto, caleado a 50% ST - biossólido (equivalentes a 0, 60, 100, 200, 250 e 300 kg N ha-1), sobre a ...
Juarez P. Pedroza +4 more
doaj +1 more source
Graphical Abstract and Lay Summary We designed a novel bioreactor system to improve large‐scale cell production for advanced therapies. It ensures uniform cell growth conditions, efficient harvesting, and easy scalability. This innovation could significantly enhance the manufacturing efficiency and accessibility of cell and gene therapy.
Vasiliy N. Goral +17 more
wiley +1 more source
Mutational spectrum and genotype–phenotype correlation in a large case series of Pompe disease in Mexico with identification of two novel gene variants not reported previously. Abstract Background Pompe Disease (PD) is a metabolic myopathy caused by variants in the GAA gene, resulting in deficient enzymatic activity.
Valentina Martinez‐Montoya +25 more
wiley +1 more source
Objetivou-se avaliar a variabilidade e herdabilidade de caracteres quantitativos relacionados à qualidade de forragem de 32 clones de capim-elefante (três testemunhas locais, da Zona da Mata de Pernambuco, e os demais provenientes da RENACE/CNPGL ...
Antônio Luiz Cordeiro da Silva +7 more
doaj +1 more source
Aims The hollow‐fibre system for tuberculosis (HFS‐TB) is a preclinical model qualified by the European Medicines Agency to underpin the anti‐TB drug development process. It can mimic in vivo pharmacokinetic (PK)–pharmacodynamic (PD) attributes of selected antimicrobials, which could feed into in silico models to inform the design of clinical trials ...
Diana A. Aguilar‐Ayala +10 more
wiley +1 more source
A conservação ambiental é uma pauta política atual e prioritária, que envolve múltiplos campos do conhecimento. Fundamentados na racionalidade ambiental, que considera que o tema não é privilégio das ciências da natureza, este artigo apresenta uma visão
Raphael Melazzo de Faria Costa +3 more
doaj +1 more source
Foram realizados dois experimentos, o primeiro com o objetivo de avaliar o efeito da substituição do feno de capim-elefante por palma forrageira e o segundo para avaliar o efeito da substituição total do milho, e parcial da soja, por palma e ureia sobre ...
Safira Valença Bispo +5 more
doaj +1 more source
Plant‐based meat analogues marketed in Catalonia: evaluation of the nutritional profile
Abstract In later years, a growing trend is apparent of vegetarian or vegan diets attributable to a number of causes, among of others, consumers’ concern for animal welfare, climate change and, to a lesser degree, for health‐related issues. On a par to this growth, availability of meat analogues in the market has also been on the rise. In this context,
Judit Costa Català +4 more
wiley +1 more source
Generation of stable suspension producer cell lines for serum‐free lentivirus production
Graphical Abstract and Lay Summary Lentiviral vectors (LVs) are widely used for gene and cell therapies, but process yields are limited by traditional production methods like transient transfection and cytotoxic effects of some expressed vector components.
Maximilian Klimpel +21 more
wiley +1 more source

