Results 121 to 130 of about 196,550 (300)
Advanced Science, EarlyView.Osteosarcoma stemness is driven by the ITGB2‐COPS3‐SOX2 signaling axis. This study reveals that nuclear COPS3 stabilizes SOX2, which in turn undergoes liquid‐liquid phase separation to promote stemness. Based on this mechanism, a novel COPS3 inhibitor, Z‐5891, was developed, effectively suppressing tumor growth and stemness in vivo, offering a ...
Lei Guo +7 more
wiley +1 more source
Piperazine‐Functionalized Nanoparticles Enable Oral Insulin Delivery in Obese Mice
Advanced Science, EarlyView.ABSTRACT Biologics have gained prominence as a rapidly advancing therapeutic modality for a diverse spectrum of medical conditions. Nonetheless, they are predominantly administered parenterally due to poor absorption through the gastrointestinal tract. Additionally, repeated injections of biologics such as insulin cause injection pain, leading to dose ...
Yuxue Cao +14 more
wiley +1 more source
Advanced Science, EarlyView.Fe‐rich NiFe‐LDH catalysts derived from MOFs, showing superior OER activity via lattice oxygen mechanism activation. ABSTRACT Developing a durable and efficient oxygen evolution reaction (OER) catalyst without noble metals is essential for the economical and sustainable production of hydrogen by alkaline water electrolysis.
Nithinraj Panangattu Dharmarajan +12 more
wiley +1 more source
Advanced Science, EarlyView.Schematic showing a stretchable triboelectric nanogenerator based on interlocked wavy architectures that uses EGaIn microflower‐embedded PVDF‐TrFE and Nylon‐6 nanofiber membranes. The multi‐petaled, electron‐rich EGaIn microflowers enhance interfacial polarization and capacitance, while the interlocked wavy architecture enlarges the effective contact ...
Qianqian Xu +12 more
wiley +1 more source
The ideal-valued index of fibrations between $G_2$ flag manifolds [PDF]
, 2021 Noé Bárcenas, Jaime Calles
openalex
Fast algorithm to identify minimal patterns of synchrony through fibration symmetries in large directed networks. [PDF]
Chaos, 2022 Monteiro HS +4 more
europepmc +1 more source
Advanced Science, EarlyView.ABSTRACT The combination of metasurfaces with chalcogenide phase‐change materials is a highly promising route toward the development of multifunctional and reconfigurable nanophotonic devices. However, their transition into real‐world devices is hindered by several technological challenges. This includes, amongst others, the lack of large area photonic
Carlota de Ruiz de Galarreta +8 more
wiley +1 more source
Dislocations and fibrations: the topological structure of knotted defects in smectic liquid crystals
New Journal of PhysicsIn this work, we investigate the topological properties of knotted defects in smectic liquid crystals. Our story begins with screw dislocations, whose radial surface structure can be smoothly accommodated on S ^3 for fibred knots by using the ...
Paul G Severino +2 more
doaj +1 more source