Results 291 to 300 of about 578,532 (358)

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology

open access: yesNature Genetics, 2018
J. Nielsen   +48 more
semanticscholar   +1 more source

Use of Real‐World Claims Data to Assess the Prevalence of Concomitant Medications to Inform Drug–Drug Interaction Risk in Target Patient Populations

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
A common issue in clinical drug development involves drug–drug interactions (DDI) that may lead to altered drug exposure and subsequent altered safety and efficacy of an investigational drug or concomitant medications (conmeds) in the target patient population.
Alice S. Tang   +6 more
wiley   +1 more source

Ventricular Response in Atrial Fibrillation

open access: bronze, 1965
Richard Langendorf   +2 more
openalex   +1 more source

Impact of Age and Factor Xa Inhibitor Concentrations on Bleeding Risk in Patients with Atrial Fibrillation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
This study aimed to analyze differences in the exposure‐response relationship for factor Xa inhibitors (FXaI) between patients aged ≥ 80 and < 80 years. Patients with atrial fibrillation (AF) taking rivaroxaban, apixaban, or edoxaban were enrolled, and a single steady‐state trough concentration was measured.
Shin‐Yi Lin   +7 more
wiley   +1 more source

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