Results 91 to 100 of about 2,560 (174)
FASEB BioAdvances, Volume 8, Issue 3, March 2026.We enrolled a pediatric sepsis cohort at acute and recovery phases for plasma proteomics analysis. Abundantly expressed proteins in sepsis were identified and subjected to machine learning. In addition, the data was compared to adult sepsis and sterile inflammation.
Fahd Alhamdan +7 more
wiley +1 more source
Cancer Science, Volume 117, Issue 3, Page 711-726, March 2026.This study investigates the role of Sushi domain‐containing 2 (SUSD2) in pancreatic ductal adenocarcinoma (PDAC) and demonstrates that SUSD2 enhances both metastasis and primary tumor growth by promoting integrin β1–FAK signaling. SUSD2 interacts with integrin β1, enhancing adhesion to extracellular matrix (ECM) components such as collagen 1 and ...
Junjiro Yoshida +11 more
wiley +1 more source
The function of miRNA in cardiac hypertrophy [PDF]
, 2012 Cardiac hypertrophy is an adaptive enlargement of the myocardium in response to altered stress or injury. The cellular responses of cardiomyocytes and non-cardiomyocytes to various signaling pathways should be tightly and delicately regulated to maintain
Jian Wang, Xiao Yang
core +1 more source
Immunology &Cell Biology, Volume 104, Issue 3, Page 276-311, March 2026.In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Kerrie L Foyle +6 more
wiley +1 more source
Specialization of tendon mechanical properties results from interfascicular differences [PDF]
, 2012 Tendons transfer force from muscle to bone. Specific tendons, including the equine superficial digital flexor tendon (SDFT), also store and return energy.
Alexander R. M. +8 more
core +1 more source
Plant Biotechnology Journal, Volume 24, Issue 3, Page 1898-1915, March 2026.ABSTRACT High‐temperature stress severely threatens rice (Oryza sativa L.) growth and productivity, particularly during the seedling stage, making heat tolerance an essential breeding target. In this study, we identified the heat shock transcription factor OsHsfc1a as a positive regulator of thermotolerance in rice seedlings.
Jingqin Lu +11 more
wiley +1 more source
Extracellular deposition of matrilin-2 controls the timing of the myogenic program during muscle regeneration. [PDF]
, 2014 Here, we identify a role for the matrilin-2 (Matn2) extracellular matrix protein in controlling the early stages of myogenic differentiation. We observed Matn2 deposition around proliferating, differentiating and fusing myoblasts in culture and during ...
Deák, F. +14 more
core +1 more source
, 2014 Why only 20% of smokers develop clinically relevant chronic obstructive pulmonary disease (COPD) was a puzzle for many years. Now, epidemiologic studies point clearly toward a large heritable component.
Lomas, David A, Marciniak, Stefan J
core +1 more source
Fibrillin–integrin interactions in health and disease
Biochemical Society Transactions, 2008 Human fibrillin-1 is the major structural protein of extracellular matrix 10–12 nm microfibrils. It has a disulfide-rich modular organization which consists primarily of cbEGF (Ca2+-binding epidermal growth factor-like) domains and TB (transforming growth factor β-binding protein-like) domains.
Jovanovic, J +4 more
openaire +4 more sources
Dual targeting of a mature plastoglobulin/fibrillin fusion protein to chloroplast plastoglobules and thylakoids in transplastomic tobacco plants [PDF]
, 2017 Plastoglobules (PG) are lipid droplets in chloroplasts and other plastid types having important functions in lipid metabolism. Plastoglobulins (PGL) also known as fibrillins (FBN) are evolutionary conserved proteins present at the PG surface but also ...
Besagni, Céline +6 more
core