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Organization and Biomechanical Properties of Fibrillin Microfibrils
2004The evolution and function of multicellular organisms has required tissue flexibility and the necessity to withstand stretch. These properties underpin movement and allow responses to changing environments. The elastic fibre is a bio-composite material composed of two insoluble extracellular matrix assemblies; fibrillin-rich microfibrils and elastin ...
Kielty, C M +5 more
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Abnormalities of fibrillin in acquired cutis laxa
Journal of the American Academy of Dermatology, 1994Degeneration of elastic tissue in acquired cutis laxa has been previously described, but microfibrils have not been adequately studied.We determined whether the microfibrillar component of elastic tissue is affected in skin of a patient with acquired cutis laxa.Lesional skin was examined with indirect immunofluorescence and immunoelectron microscopy ...
M G, Lebwohl +5 more
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The structure and function of fibrillin.
Ciba Foundation symposium, 1996Fibrillin is a very large molecule whose primary structure is now known from the cloning and sequencing of 10 kb of cDNA. Immunohistochemical results suggest that one of the functions of fibrillin molecules is to contribute to the structure of the microfibril.
D P, Reinhardt +2 more
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The Role of Fibrillin 1 and Fibrillin 2 in Severe Scoliosis
1999Child A +5 more
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