Results 41 to 50 of about 52,394 (202)

Hemocompatible Glycogen‐Tissue Plasminogen Activator Complexes for Enhanced Blood Clot Dissolution

Advanced Healthcare Materials, EarlyView.
Glycogen–heparin‐cRGD nanoparticles enable targeted delivery of tissue plasminogen activator (tPA) to thrombi through activated platelet recognition. The hemocompatible hybrids minimize interactions with blood and immune cells while retaining enzymatic biodegradability.
Nadiia Davydiuk, Vaidehi Londhe, Susanne Boye, Martin Müller, Carsten Werner, Manfred F. Maitz, Quinn A. Besford   +6 more
wiley   +1 more source

Use of a Fibrin Sealant Patch at Cesarean for Conservative Management of Morbidly Adherent Placenta

American Journal of Perinatology Reports, 2018
Background Morbidly adherent placenta represents a surgical challenge and source of maternal morbidity and mortality. We report the use of a fibrin sealant patch to address hemorrhage associated with a morbidly adherent placenta during cesarean delivery.
James A. Greenberg, Julian N. Robinson, Jean M. Carabuena, Michaela K. Farber, Daniela A. Carusi   +4 more
doaj   +1 more source

Hybrid Biofabrication of a Hierarchically Organized Periosteum‐Inspired In Vitro Platform

Advanced Healthcare Materials, EarlyView.
A hybrid biofabrication strategy integrates melt electrowriting with extrusion‐based 3D bioprinting to create a hierarchically organized periosteum‐inspired in vitro platform. Spatially defined osteogenic, fibrous, and endothelial cell‐containing compartments support long‐term culture, osteogenic maturation, and CD31+ endothelial cell organization ...
Yakui Liu, Xinggui Tian, Anne Bernhardt, Anja Lode, Max von Witzleben, Ege Kirbas, Stefan Zwingenberger, Michael Gelinsky   +7 more
wiley   +1 more source

Fibrin versus polyethylene glycol sealant: an experimental study in rabbits [PDF]

, 2008
Fibrin glue has been applied universally in general surgery as an adhesive, hemostatic, or embolizing agent. In reconstructive surgery, fibrin has been used mainly for nerve and microvascular repair or as a substitute for sutures in skin closure and skin
Schneller, Maria, Gertrude M. Beer, Hug, Urs, Cristina-Schmitz, Heidi, Mihic-Probst, Daniela, Maria Schneller, Beer, Gertrude M, Heidi Cristina-Schmitz, Daniela Mihic-Probst, Urs Hug   +9 more
core   +1 more source

Microfluidic Droplet Plate Preserving Single Human Induced Pluripotent Stem Cell‐Derived Cardiomyocytes Morphology and Function

Advanced Materials Technologies, EarlyView.
We introduce a novel method combining microfluidics, optogenetics, and human induced pluripotent stem cell (iPSC) technology to encapsulate single iPSC‐derived cardiomyocytes (iPSC‐CMs) in an optimal environment for functional characterization. This method enables direct genotype‐phenotype correlation for genetic studies and high‐throughput screening ...
Xiao‐Ting Wang, Rachel P. White, Yashasvi Tharani, Michael A. Finocchiaro, Leona M. Ripple, Maksymilian Prondzynski, Tania Konry, Vassilios J. Bezzerides   +7 more
wiley   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

Autologous fibrin glue: automated production and adhesive quality

Current Directions in Biomedical Engineering, 2017
Fibrin glue is a two-component adhesive used to stop bleeding, seal wound edges and for scaffolds in tissue engineering. Autologous products result in reduced risk of contamination and immunological responses compared to commercially available fibrin ...
Düregger Katharina, Frenzel Sabrina, Eblenkamp Markus   +2 more
doaj   +1 more source

The Use of Fibrin Sealant in Facelift Surgery

, 2002
Purpose: To report the use of fibrin sealant in facelift surgery. Methods: A prospective study of 40 individuals was performed comparing individuals undergoing facelift surgery with and without the use of fibrin sealant.
John J. Fezza, Mont J. Cartwright, Patrick Flaharty, William Mack   +3 more
core   +1 more source

The efficacy of fibrin sealant patches in reducing the incidence of lymphatic morbidity after radical lymphadenectomy: A meta-analysis [PDF]

, 2017
BACKGROUND Although pivotal in the oncological management of most tumors, radical lymphadenectomy is associated with a significant number of lymphatic complications.
Mueller, Michael, Papadia, Andrea, Ilary Ruscito, Andrea Papadia, Bolla, Daniele, Pierluigi Benedetti Panici, Benedetti Panici, Pierluigi, Mueller, Michael D., Maria Luisa Gasparri, Gasparri, Maria Luisa, Ruscito, Ilary, Michael D. Mueller, Daniele Bolla, Mueller MD, Bolla D, Benedetti Panici P, Ruscito I, Papadia A, Gasparri ML   +18 more
core   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source