Molecular pathology of phyllodes tumours of the breast-much more than MED12. [PDF]
Phyllodes tumours can develop from fibroadenomas bearing MED12 variants by the development of pTERT alterations (“MED12 pathway”) or de novo (“MED12 independent pathway”). Grade progression is associated with increasing genetic complexity including cancer driver gene aberrations. Molecular alterations can be useful in assigning grade and distinguishing
Pang JB, Gorringe KL, Tan PH, Fox SB.
europepmc +2 more sources
Intracavernous and Intravenous Use of Contrast-Enhanced Ultrasound in Children: A Report of Five Cases and Review of the Literature. [PDF]
Pediatric Discovery, Volume 4, Issue 1, March 2026.
You Y +5 more
europepmc +2 more sources
Transformation of benign fibroadenoma to malignant phyllodes tumor
The transformation of a benign fibroadenoma into a phyllodes tumor is uncommon and unpredictable. We report the case of a 40-year-old woman with a core biopsy proven fibroadenoma that underwent transformation into a malignant phyllodes tumor after 3 ...
Linda M Sanders +3 more
doaj +2 more sources
Rapid and Accurate Diagnosis of Breast Cancer by Fine-Needle Aspiration Biopsy Using the "Click-to-Sense" Method. [PDF]
ABSTRACT Background We have previously demonstrated the value of the “click‐to‐sense” (CTS) assay, in which a fluorescent probe targeting acrolein can detect cancer cells and differentiate between malignant and benign lesions in breast tissue. In this study, we assessed the usefulness of the CTS assay for diagnosis of breast tumors by fine‐needle ...
Kitahara Y +17 more
europepmc +2 more sources
Fibroadenoma in a young male breast: A case report and review of the literature
Fibroadenomas are the most common benign breast tumors in women, but rarely occur in men. Herein, we present a case of fibroadenoma occurring in a young, healthy male without hormonal alterations.
Hiroki Morikawa +11 more
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Juvenile Fibroadenoma Detected at 2 Years and Rapid Growth at Thelarche: Case Report and Literature Review [PDF]
Juvenile fibroadenoma typically is seen in the adolescent patient and has distinctive clinical and histopathological features that are related to the early onset of the benign tumor.
Benedikt Schaefgen +2 more
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Intraductal fibroadenoma presenting with nipple bleeding in an adolescent: a case report and literature review [PDF]
A 12-year-old Chinese adolescent girl presented with a 2-month history of left nipple bleeding. Physical examination revealed bloody and brownish nipple discharge.
Pingfa Gao +5 more
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Feasibility and efficacy of microwave ablation for treating breast fibroadenoma
Background To investigate the safety, efficacy, and follow-up outcomes of microwave ablation (MWA) in patients with breast fibroadenoma. Methods An institutional review board-approved this study of patients treated with MWA for breast fibroadenoma from ...
Gang Liu +6 more
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Objective To provide an accurate assessment of the prevalence of breast fibroadenoma in a large population and to confirm the diagnostic accuracy of ultrasound for fibroadenoma.Design This was a cross-sectional survey.Setting This research was conducted ...
Yingjia Li +7 more
doaj +1 more source
Demographic characteristics and body mass index in women with breast fibroadenoma and compare with healthy women referred to Khatam Al-Anbia Clinic in Jahrom in 2019 [PDF]
Introduction: Benign breast diseases are one of the most common diseases in the females of any society. This study was performed with aim to determine demographic characteristics, history of disease and body mass index in women with benign breast masses ...
Marzieh Haghbin +2 more
doaj +1 more source

