Results 311 to 320 of about 1,131,844 (424)

Engineered Chitosan‐Derived Nanocarrier for Efficient siRNA Delivery to Peripheral and Central Neurons

Advanced Healthcare Materials, EarlyView.
This study introduces a novel chitosan‐based nanocarrier functionalized with a neurotropic protein for efficient siRNA delivery to neurons. The polyplexes demonstrate enhanced neuronal binding, retrograde transport, and PTEN silencing, promoting axonal outgrowth.
Ana P. Spencer, Adriana Vilaça, Miguel Xavier, Rafael Santos, Ariel Ionescu, María Lázaro, Victoria Leiro, Eran Perlson, Sofia C. Guimarães, Ben M. Maoz, Ana P. Pêgo   +10 more
wiley   +1 more source

Identifying a Role for the Sodium Hydrogen Exchanger Isoform 1 in Idiopathic Pulmonary Fibrosis: A Potential Strategy to Modulate Profibrotic Pathways. [PDF]

Biomedicines
Nguyentu TT, Vigilante DG, Manchanda M, Iyer MS, Desalegne S, Provost JJ.   +5 more
europepmc   +1 more source

Stndies on the Treatment of Malignant Tumors with Fibroblast-Inhibiting Agent

, 1965
Hidenari Kodani
openalex   +2 more sources

Tri‐Layered Bioactive Cutaneous Scaffold with Integrated Bioactive Metal Organic Frameworks to Promote Full‐Thickness Infected Diabetic Wound Healing: Multifaceted Therapeutic Strategies

Advanced Healthcare Materials, EarlyView.
The limitations of existing clinical treatments highlight the need for a more comprehensive strategy for addressing infected diabetic wounds. A tri‐layered scaffold is developed to deliver therapeutics loaded in CuBDC and ZIF‐8 MOFs that are tailored to the requirements of deep‐infected diabetic wounds.
Ayse Gunyakti Mujtaba, Ayşe Karakeçili, Berna Topuz, Barış Batur, Okan Onar, Mehmet Eray Elçiğir, Çağdaş Oto, Alireza Hanifehnezhad, Kaan Orhan   +8 more
wiley   +1 more source

PGC-1α mediates migrasome secretion accelerating macrophage-myofibroblast transition and contributing to sepsis-associated pulmonary fibrosis. [PDF]

Exp Mol Med
Peng Y, Mei S, Qi X, Tang R, Yang W, Feng J, Zhou Y, Huang X, Qian G, Xing S, Gao Y, Xu Q, He Z.   +12 more
europepmc   +1 more source

Biohybrid Vascular Graft Made of Textile‐Reinforced Elastin‐Like Recombinamers and Its Preservation via Drying Processes

Advanced Healthcare Materials, EarlyView.
Clinical translation of biohybrid medical implants requires the previous implementation of drying schemes that can facilitate their sterilization and storage. This study addresses that critical aspect and elucidates the impact of drying on biohybrid vascular grafts, highlighting the need for implant‐specific drying strategies to ensure safety ...
Dominic Pascal Andre, Stephan Ruetten, José Carlos Rodríguez‐Cabello, Stefan Jockenhoevel, Thomas Schmitz‐Rode, Alicia Fernández‐Colino   +5 more
wiley   +1 more source

Analysis of cellular responses following interaction with extracellular vesicles derived from HEK293T and human adipose derived stem cells. [PDF]

Sci Rep
Zhang W, Obuchi S, Teramura Y.
europepmc   +1 more source

Light‐Activatable Hyaluronic Acid‐Derivatives Releasing Nitric Oxide and Their Delivery in the Skin

Advanced Healthcare Materials, EarlyView.
This work explores the development of photoactivatable hyaluronic acid (HA) derivatives functionalized with nitric oxide (NO) photodonors for light‐controlled therapeutic applications. The HA derivatives demonstrate enhanced keratinocyte proliferation and migration, effective NO release, and skin penetration when formulated as microemulsions.
Giuseppe Longobardi, Cristina Parisi, Federica Sodano, Ovidio Catanzano, Anna Di Porzio, Antonio Randazzo, Salvatore Sortino, Fabiana Quaglia   +7 more
wiley   +1 more source

Lactobacillus reuteri NCHBL-005 improves wound healing by promoting the activation of fibroblasts through TLR2/MAPK signaling. [PDF]

Inflamm Regen
Kim DY, Lee TS, Lee YJ, Ahn SY, Chu B, Jung DH, Kim YJ, Seo IS, Kim WG, Cho YJ, Hong JJ, Park JH.   +11 more
europepmc   +1 more source

Pericyte–fibroblast transition promotes tumor growth and metastasis

Proceedings of the National Academy of Sciences of the United States of America, 2016
K. Hosaka, Yunlong Yang, T. Seki, Carina Fischer, O. Dubey, E. Fredlund, J. Hartman, P. Religa, Hiromasa Morikawa, Y. Ishii, M. Sasahara, O. Larsson, G. Cossu, R. Cao, Sharon Lim, Yihai Cao   +15 more
semanticscholar   +1 more source