Results 351 to 360 of about 2,052,125 (407)
Some of the next articles are maybe not open access.
The FASEB Journal, 1987
Fibroblast growth factors (FGFs) are heparin-binding protein mitogens that induce division of most cultured cells derived from embryonic mesoderm and neuroectoderm. Terminally differentiated neurons also respond in vitro by eliciting outgrowth of neurites.
openaire +2 more sources
Fibroblast growth factors (FGFs) are heparin-binding protein mitogens that induce division of most cultured cells derived from embryonic mesoderm and neuroectoderm. Terminally differentiated neurons also respond in vitro by eliciting outgrowth of neurites.
openaire +2 more sources
Receptors for fibroblast growth factors
Immunology & Cell Biology, 1995SummaryThe recent discovery of the involvement of heparan sulfate proteoglycans (HSPG) in the activation of fibroblast growth factor receptors (FGFR) has led to an intensification of study of this field. It appears that the HSPG act as low affinity receptors to which the fibroblast growth factors (FGF) must bind in order to successfully activate the ...
John T Gallagher, Jacqueline C Coutts
openaire +3 more sources
Fibroblast growth factors and their receptors in cancer.
Biochemical Journal, 2011FGFs (fibroblast growth factors) and their receptors (FGFRs) play essential roles in tightly regulating cell proliferation, survival, migration and differentiation during development and adult life. Deregulation of FGFR signalling, on the other hand, has
J. Wesche, K. Haglund, E. M. Haugsten
semanticscholar +1 more source
Inhibition of fibroblast growth factors
Breast Cancer Research and Treatment, 1996The potential roles of members of the fibroblast growth factor family in tumor angiogenesis and metastasis and their mechanisms of release from cells are discussed. Furthermore, we review methods of therapeutic targeting of these polypeptides. In particular, we focus on the possibility to inhibit fibroblast growth factors with drugs that mimic heparin ...
Frank Czubayko, Anton Wellstein
openaire +3 more sources
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2013
There is growing interest in the role of fibroblast growth factor 23 (FGF23) in various diseases of disordered mineral metabolism. In chronic kidney disease (CKD), where biochemical evidence of mineral disturbances is especially common, FGF23 measurement has been advocated as an early and sensitive marker for CKD-related bone disease. In this setting,
Stephen G Holt +3 more
openaire +3 more sources
There is growing interest in the role of fibroblast growth factor 23 (FGF23) in various diseases of disordered mineral metabolism. In chronic kidney disease (CKD), where biochemical evidence of mineral disturbances is especially common, FGF23 measurement has been advocated as an early and sensitive marker for CKD-related bone disease. In this setting,
Stephen G Holt +3 more
openaire +3 more sources
Initiation of mammalian liver development from endoderm by fibroblast growth factors.
Science, 1999The signaling molecules that elicit embryonic induction of the liver from the mammalian gut endoderm or induction of other gut-derived organs are unknown.
Joo-Un Jung +3 more
semanticscholar +1 more source
Fibroblast growth factor and hydrocephalus
Neurological Research, 2000The immunohistochemical localization of basic fibroblast growth factor (bFGF) was studied in ventricular ependyma and choroid plexus of aged-matched normotensive and spontaneously hypertensive rats at different ages using a polyclonal antibody against bFGF.
G Giménez-Gallego, P Cuevas
openaire +3 more sources
Fibroblast Growth Factor Prototype Release and Fibroblast Growth Factor Receptor Signaling
Thrombosis and Haemostasis, 1999A Brief Introduction to the Fibroblast Growth Factor Gene Family The fibroblast growth factor (FGF) family of genes presently comprise 18 members, including the two prototypes, FGF-1 (acidic) and FGF-2 (basic). Although the FGF prototypes are well described as mediators of a variety of diverse biological responses, such as mesoderm induction ...
Thomas Maciag, Robert Friesel
openaire +3 more sources
1996
Recent advances in the field of fibroblast growth factors (FGF) have led to a better understanding of their physiological functions and their roles in the pathogenesis of disease. In reviewing this field, we have concentrated on the numerous recent advances suggesting that these molecules are pivotal in embryonic development, reproduction, growth ...
Andrew Baird, Ann Logan
openaire +2 more sources
Recent advances in the field of fibroblast growth factors (FGF) have led to a better understanding of their physiological functions and their roles in the pathogenesis of disease. In reviewing this field, we have concentrated on the numerous recent advances suggesting that these molecules are pivotal in embryonic development, reproduction, growth ...
Andrew Baird, Ann Logan
openaire +2 more sources
Biochemistry, 1985
Two retina-derived growth factors have been isolated on the basis of their ability to stimulate the proliferation of capillary endothelial cells in vitro. Gas-phase sequence analysis identified the amino-terminal sequence of the major form of the mitogen
A. Baird +3 more
semanticscholar +1 more source
Two retina-derived growth factors have been isolated on the basis of their ability to stimulate the proliferation of capillary endothelial cells in vitro. Gas-phase sequence analysis identified the amino-terminal sequence of the major form of the mitogen
A. Baird +3 more
semanticscholar +1 more source