Results 341 to 350 of about 988,166 (377)
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Re-evaluation of fibroblasts and fibroblast-like cells
Anatomy and Embryology, 1990Scanning electron microscopic observations of connective tissue cells show a new aspect of the nature of fibroblasts, and the subsequent broad survey of references makes clear that fibroblasts of many tissues have various features which are regarded as atypical of fibroblasts, and at the same time that various connective tissue cells in different ...
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Fibroblasts in the Tumor Microenvironment
2020The implications of a tumor microenvironment in cancer initiation and progression have drawn interest in recent years. Within the tumor stroma, fibroblasts represent a predominant cell type and are responsible for the majority of extracellular components within the tumor microenvironment, such as matrix and soluble factors.
Truffi M., Sorrentino L., Corsi F.
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Reduced response of scleroderma fibroblasts to fibroblast growth factor
Archives of Dermatological Research, 1984Reactivity of scleroderma fibroblasts to lymphoid cell-derived fibroblast growth factor (FGF) was assessed in this study. The fibroblasts from the sclerotic lesion failed to respond to FGF, whereas those from scleroedematous lesions responded equally to normal fibroblast.
Shigeharu Sano +3 more
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2002
Publisher Summary Fibroblasts are the most abundant cells in the lungs. They are primarily responsible for producing the extracellular matrix proteins that maintain the structure of the airways and lung parenchyma. Myofibroblasts are found in the lamina reticularis and appear as multicellular strands.
Robin J. McAnulty, Geoffrey J. Laurent
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Publisher Summary Fibroblasts are the most abundant cells in the lungs. They are primarily responsible for producing the extracellular matrix proteins that maintain the structure of the airways and lung parenchyma. Myofibroblasts are found in the lamina reticularis and appear as multicellular strands.
Robin J. McAnulty, Geoffrey J. Laurent
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2009
Publisher Summary This chapter explores the current knowledge about the role of fibroblasts in lung homeostasis and pathological disorders associated with chronic remodeling. It also reviews the potential of opportunities arising for better therapeutic intervention strategies targeting fibroblasts that will either halt or potentially reverse fibrosis.
Lynne A. Murray +2 more
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Publisher Summary This chapter explores the current knowledge about the role of fibroblasts in lung homeostasis and pathological disorders associated with chronic remodeling. It also reviews the potential of opportunities arising for better therapeutic intervention strategies targeting fibroblasts that will either halt or potentially reverse fibrosis.
Lynne A. Murray +2 more
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Clinical and Experimental Nephrology, 1998
During recent years, fibroblasts have been recognized as a heterogenous cell type with a remarkable degree of differentiation and important functional properties in health and in disease. Our better understanding of the biology of fibroblasts has elucidated some of the mechanisms responsible for fibrosis of the kidney and other organs.
Volker Becker, Gerhard A. Müller
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During recent years, fibroblasts have been recognized as a heterogenous cell type with a remarkable degree of differentiation and important functional properties in health and in disease. Our better understanding of the biology of fibroblasts has elucidated some of the mechanisms responsible for fibrosis of the kidney and other organs.
Volker Becker, Gerhard A. Müller
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Annals of the New York Academy of Sciences, 1999
ABSTRACT: We evidenced in vitro proopiomelanocortin (POMC) mRNA‐transcription in human dermal fibroblasts using Northern blot hybridization. Modulation of POMC gene expression by cytokines (transforming growth factor‐β, TGF‐β, and tumor necrosis factor‐α, TNF‐α) was investigated by incubating human normal fibroblasts with 1 and 10 ng/ml cytokines ...
Torello Lotti +3 more
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ABSTRACT: We evidenced in vitro proopiomelanocortin (POMC) mRNA‐transcription in human dermal fibroblasts using Northern blot hybridization. Modulation of POMC gene expression by cytokines (transforming growth factor‐β, TGF‐β, and tumor necrosis factor‐α, TNF‐α) was investigated by incubating human normal fibroblasts with 1 and 10 ng/ml cytokines ...
Torello Lotti +3 more
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2007
Extensive research has shown that connective tissues such as tendons and ligaments are able to respond to mechanical forces by changing their structure, composition, and function. This mechanical adaptation is made possible largely by fibroblasts, the major cell types responsible for maintaining, repairing, and remodeling extracellular matrix (ECM) in ...
Bhavani P. Thampatty, James H.-C. Wang
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Extensive research has shown that connective tissues such as tendons and ligaments are able to respond to mechanical forces by changing their structure, composition, and function. This mechanical adaptation is made possible largely by fibroblasts, the major cell types responsible for maintaining, repairing, and remodeling extracellular matrix (ECM) in ...
Bhavani P. Thampatty, James H.-C. Wang
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Inhibition of fibroblast attachment
Journal of Clinical Periodontology, 1986Abstract Reattachment is at present an ephemeral goal. There is. therefore. much interest in clarifying the events which determine patterns of cellular repopulation of denuded cementum during periodontal healing, and thus determine the outcome of reattachment surgery.
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American Journal of Respiratory and Critical Care Medicine, 2006
Anna Luise A Katzenstein +1 more
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Anna Luise A Katzenstein +1 more
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