Multi-Mechanistic Effects of Xylopia aethiopica Fruits on Uterine Fibroids: Insights From In Vivo and In Silico Evidence. [PDF]
Xylopia aethiopica fruit extract modulates progesterone and estradiol levels in monosodium glutamate‐induced uterine fibroid models. In silico analyses reveal strong binding of its phytochemicals to progesterone, estrogen, VEGFR2, and TGF‐β receptors, indicating multi‐target anti‐fibroid actions involving hormonal regulation, anti‐angiogenesis, and ...
Oluwasegun A +7 more
europepmc +2 more sources
Good news: A long-awaited model for uterine fibroid tumor research is upon us (1). Historically, there has been a paucity of in vivo models for the study of fibroid tumors (i.e., leiomyomas), benign female pelvic organ tumors characterized by clonal proliferation of smooth muscle cells and expression of genes involved in fibrosis and extracellular ...
Bo R, Rueda, John S, Davis
openaire +2 more sources
Intravenous tranexamic acid as an adjunct haemostat to ornipressin during open myomectomy. A randomized double blind placebo controlled trial [PDF]
Myomectomy is a surgical technique used for removal of uterine fibroids and historically hysterectomy has represented the mainstay of treatment. The options of conservative surgical approaches mainly aim at retention of fertility but have to be balanced ...
Ngichabe, Sammy +5 more
core +1 more source
Objective To investigate the associations between serum vitamin D, calcium and uterine fibroids in a Chinese female population. Methods In this case-control study, adult female patients with fibroids (cases) were compared with females without fibroids ...
Saisai Li +4 more
doaj +1 more source
Uterine Fibroids (Leiomyoma, Myoma) [PDF]
Uterine fibroids (leiomyomas, myomas) are the most common tumor formations of the uterus. These are tumors with benign potential and the occurrence of malignancy or finding of leiomyosarcoma is rare. Fibroids can occur in any part of the uterus.
Petanovski, Zorancho, Kurjak, Asim
core +2 more sources
A survey on the current practice of indicating an elective cesarean after a previous myomectomy
Objective The objective of this study was to evaluate the attitude of obstetricians/gynecologists toward indicating an elective cesarean delivery in pregnant patients with a previous myomectomy.Materials and Methods Web-based multiple-choice questions ...
Giovanni Delli Carpini +7 more
doaj +1 more source
Objective To investigate the application value of acoustic radiation force impulse imaging in preoperative prediction for efficacy of High-Intensity Focused Ultrasound uterine fibroids ablation Methods A prospective study was conducted on 32 women (41 ...
Dan-ling Zhang +7 more
doaj +1 more source
Noninvasiv sebészet MR-vezérelt fókuszált ultrahanggal: állatkísérletes modellek és klinikai tapasztalatok = Noninvasive surgery using MR-guided focused ultrasound: animal models and clinical experience [PDF]
Az MR vezérelt fókuszált ultrahang sebészet (MRgFUS) noninvasiv módon képes a szervezet belsejében daganatos sejteket elpusztítani. Kutatásainkban 1.) állatkísérletes modellen vizsgáltuk az ultrahang kontrasztanyag potencírozó szerepét, valamint 2 ...
Bajzik, Gábor +5 more
core +1 more source
The role of atorvastatin in suppressing tumor growth of uterine fibroids
Background Medical therapeutic options remain quite limited for uterine fibroids treatment. Statins, competitive inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, have anti-tumoral effects on multiple cancer types, however, little is known ...
Zhaojun Shen +6 more
doaj +1 more source
Perception and Health Care Seeking Behaviors of Women with Uterine Fibroids [PDF]
Background: Uterine fibroids are benign tumors that impact the women's uterus during childbearing years. Perception and health care seeking behaviors of women with uterine fibroids can have major effects on their overall health, quality of life, and ...
Walaa Elseady +3 more
doaj +1 more source

