Results 91 to 100 of about 42,483 (237)

Efficacy and Safety of Cannabis Derivates and Their Synthetic Analogs. Overview of Systematic Reviews

Phytotherapy Research, EarlyView.
ABSTRACT The use of medicinal products derived from cannabis and its synthetic analogues has grown in recent years for various health conditions, which led to an increase in systematic reviews (SR) on the topic. The objective of this overview was to identify, synthesize, and critically appraise the evidence from SR on the benefits and harms of cannabis
Rafael Leite Pacheco, Daniela Fortunato Rêgo, Carolina de Oliveira Cruz Latorraca, Marco Aurelio de Carvalho Nascimento, André Bastos Daher, Rachel Riera   +5 more
wiley   +1 more source

Exploratory MRI and Clinical Marker Analysis of Pustulotic Arthro‐Osteitis Disease Activity From a Phase 3 Brodalumab Trial

The Journal of Dermatology, EarlyView.
ABSTRACT Pustulotic arthro‐osteitis (PAO) is a clinically important osteoarticular comorbidity affecting approximately 9%–28% of patients with palmoplantar pustulosis (PPP), yet early recognition and standardized activity assessment remain challenging, particularly in routine dermatology practice.
Taiki Nozaki, Manabu Arai, Junko Ochi, Mona Uchida‐Yamada, Masahiro Hashimoto, Mitsuhiro Akiyama, Yuko Kaneko, Yasumasa Kanai, Masahiro Jinzaki   +8 more
wiley   +1 more source

“Swallowed by a Black Hole”: The Neglected Impact of Endometriosis in the Workplace

Human Resource Management Journal, EarlyView.
ABSTRACT This study examines how endometriosis, as a chronic and cyclical condition, is experienced and managed in contemporary workplaces, and what this reveals about the limits of existing human resource management (HRM) frameworks. Drawing on Feminist Disability Theory (FDT), we conceptualise endometriosis as a form of structurally produced ...
Meltem Yavuz Sercekman, Ozlem Ayaz
wiley   +1 more source

Effect of Anti‐IL‐23 and Anti‐IL‐17 Therapy on Darier Disease: A Case Series

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Darier disease is a rare ATP2A2‐related genodermatosis for which therapeutic options remain limited, as acitretin is often constrained by toxicity and teratogenicity. In this retrospective real‐world case series of eight patients, anti‐IL‐17 therapy showed a more consistent early signal of clinical benefit than anti‐IL‐23 therapy, with greater
Maione Vincenzo, Zanghi Silvia, Catapano Cecilia, Bighetti Stefano, Cattaneo Isacco, Venturini Marina, Bettolini Luca   +6 more
wiley   +1 more source

Treatment of fibromyalgia [PDF]

Australian Prescriber, 2017
Fibromyalgia is a common, often overlooked, clinical syndrome in general practice. It can be associated with considerable disability, but this is likely to be minimised by early diagnosis and intervention. Patients with fibromyalgia often have other chronic conditions.
openaire   +2 more sources

Self‐Reported Health Problems of Birthing Persons During the First and Second Postpartum Years: Scope and Correlates

Birth, EarlyView.
ABSTRACT Background Postpartum health‐related problems are diverse, and some may extend beyond the first postpartum year. The purpose of this study was to describe women's postpartum health problems in the first and second postpartum years. Methods We analyzed data from an online survey (N = 427) conducted in 2024.
Sudhathai Sirithepmontree, Lina Palomares, Lorraine O. Walker   +2 more
wiley   +1 more source

Symptom management and lifestyle interventions for people with fibromyalgia

Advanced Exercise and Health Science
Fibromyalgia is a complex condition with symptoms of hyperalgesia, chronic fatigue, anxiety and depression. Treating fibromyalgia symptoms typically requires pharmacological, psychological and lifestyle interventions to reduce the impact of the disease ...
Cara E. Brown, André R. Nelson
doaj   +1 more source

Sleep hygiene and sleep control mediate the relationship between cognitive fusion and insomnia severity

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives Insomnia is associated with mental ill health, worry and rumination—the two latter contribute to pre‐sleep cognitive arousal. These variables also associate with psychological inflexibility, including cognitive fusion (CF), a literal attachment to unhelpful thoughts, patterns and rules.
Amanda L. Richdale, Francesco R. De Maria, Eric M. J. Morris   +2 more
wiley   +1 more source

Alkalinised lidocaine as an anaesthetic before onabotulinumtoxinA injections. a randomised trial

BJU International, Volume 135, Issue 4, Page 638-647, April 2025.
Objectives To evaluate the effect of intravesical alkalinised lidocaine as an anaesthetic treatment on procedural pain during intradetrusor onabotulinumtoxinA (BTX‐A) injections for overactive bladder. Patients and Methods This single‐centre, randomised, double‐blind, placebo‐controlled two period crossover trial was conducted on women scheduled for ...
Meryam El Issaoui, Marlene Elmelund, Niels Klarskov   +2 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source