Nascent Extracellular Matrix Converts Biomaterial Cues into Cell Fate Decisions
This study uncovers a tri‐directional interplay among cells, hydrogels, and their nascent extracellular matrix. Hydrogel norbornene modification alters CD44‐mediated cell–hydrogel interactions, which shape nascent matrix deposition, composition, and spatial organization.
Joshua Y. Liu +12 more
wiley +1 more source
Multi-Omics Analysis of the Effects of <i>INHA</i> and <i>FNDC1</i> on Clutch Length in Zi Geese. [PDF]
Zhao X +5 more
europepmc +1 more source
Here, a PDL1 inhibitor is employed as a fifth component to modify lipid nanoparticles (LNPs). PDL1 inhibitor‐loaded LNPs show enhanced lymph node targeting, resulting in greater lymph node expansion, immune cell infiltration, and improved mRNA vaccine efficacy. This fifth component LNP could be a novel platform for mRNA vaccines.
Minki Ha +5 more
wiley +1 more source
Effects of Single-Bout Endurance Exercise Intensity on Peripheral Neurotrophic Factors in Patients With Ischemic Stroke During the Subacute Phase of Rehabilitation. [PDF]
Górna S +3 more
europepmc +1 more source
Identification and characterization of zebrafish fibronectins
The goal of this study was to identify the fibronectin (FN) isoforms present in the zebrafish and determine their structure and pattern of expression. Sequence analysis of zebrafish FN cDNAs indicates that at least two forms of the protein exist in fish.
Zhao, Qingshun
core
Real‐Time Monitoring of Mass and Mechanical Properties in Single Cells and Multicellular Spheroids
This study introduces photothermally actuated microcantilevers combined with optical microscopy to simultaneously measure morphology, mass, and mechanical properties of cellular systems in real‐time. The findings link cytoplasm‐dominated mechanical energy dissipation to the Q‐factor as a novel biophysical parameter.
Ilaria Incaviglia +8 more
wiley +1 more source
The impact of obesity severity on oxidative stress, exercise-related biomarkers, and physical activity in type 2 diabetes: a study including subjective sleep assessment. [PDF]
Cihan E +9 more
europepmc +1 more source
Curvature‐Directed Elongation and Chiral Tilting Drive Asymmetric Tissue Patterning
Curvature and cell handedness together break tissue symmetry. On convex and concave surfaces, cells elongate along opposite geometric axes and tilt in a consistent chirality‐driven direction, yielding opposite alignment patterns from the same cells. Reversing intrinsic cell chirality reverses both.
Liyao Xu +6 more
wiley +1 more source
Evaluation of surface roughness of titanium implants on human fibroblast cells. [PDF]
Hamadani MA +10 more
europepmc +1 more source
An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He +6 more
wiley +1 more source

