Results 111 to 120 of about 65,201 (219)

The Regulation and Function of Hippo/YAP Pathway in Cancer

open access: yesThe FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Hippo/YAP pathway signaling plays critical roles in the progression of multiple cancer types. This review summarizes current knowledge of Hippo/YAP pathway regulation and function in cancer. We discuss the core components of the Hippo/YAP pathway; its crosstalk with other signaling pathways; regulation by non‐coding RNAs; roles of YAP signaling in ...
Chinmoy Ghosh   +3 more
wiley   +1 more source

Inhibition of Calcium‐Dependent Lipid Droplets Relocation of ACSL4‐PKCβ‐ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis

open access: yesAdvanced Science, Volume 13, Issue 19, 2 April 2026.
This study identifies L‐type calcium channel blockers as novel ferroptosis inhibitors. It reveals that PKCβ, activated in calcium dependent manner, phosphorylates and activates ACSL4 and ALOX15, relocating them to lipid droplets to promote lethal lipid peroxidation and ferroptosis.
Guoyuan Hou   +8 more
wiley   +1 more source

What's Your Diagnosis? Large Mediastinal Mass in a Dog

open access: yes
Veterinary Clinical Pathology, EarlyView.
Rosane O. Cruz   +7 more
wiley   +1 more source

Feeding Behaviour in the KPC Model of Pancreatic Cancer‐Associated Cachexia: Alteration of Spontaneous and Evoked Feeding Behaviours

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background The KPC mouse model of pancreatic cancer is gaining use in research, but detailed understanding of ingestive behaviour changes in this and other cachexia models is limited. Methods Male C57BL/6 J mice (7 weeks) were maintained under standard feed (PicoLab5L0D) and housing conditions (12:12 h; Light:Dark).
Fateema Muzaffar   +2 more
wiley   +1 more source

Cancer Neuroscience: Innovative Conception and Emerging Strategy of Therapy

open access: yesMedComm, Volume 7, Issue 4, April 2026.
In this review, we summarize nerve–cancer interactions and conclude two additional interactions, “perineural invasion” and “neuro‐microbic‐oncology.” Emphasizing the important role of nerves in tumor progression. The nervous system also contributes to the development of cancer comorbidities such as cancer depression and cognitive dysfunction.
Ting Wang   +5 more
wiley   +1 more source

Tumor fusocelular hialinizante con rosetas gigantes: Reporte de un caso Hyalinizing spindle cell tumor with giant rosettes: Case report

open access: yesSalud UIS, 2010
Introducción: El tumor fusocelular hialinizante con rosetas gigantes es una neoplasia constituida por dos componentes histológicos, uno celular con elementos fusiformes, y el segundo representado por islas bien delimitadas casi acelulares, llenas de ...
Ernesto García Ayala   +3 more
doaj  

Glycosaminoglycans and Glycosaminoglycan Mimetics in Cancer and Inflammation [PDF]

open access: yes, 2019
Glycosaminoglycans (GAGs) are a class of biomolecules expressed virtually on all mammalian cells and usually covalently attached to proteins, forming proteoglycans.
Morla, Shravan
core   +1 more source

Disulfide Crosslinking Induces Rapid Degradation of Arc/Arg3.1 via Hsp70‐Mediated Ubiquitin Ligase Pathway

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Heat shock induces Arc/Arg3.1 Cys34‐Cys159 disulfide crosslinking, promoting oligomerization and Hsp70‐CHIP‐dependent ubiquitination followed by proteasomal degradation during recovery. Disrupting disulfide formation (C159A) impairs CHIP‐mediated ubiquitination and stabilizes Arc/Arg3.1, whereas HSF1 loss limits inducible Hsp70 and leads to Arc ...
Dami So   +7 more
wiley   +1 more source

Comparison of Antitumour Activities of Heated and Raw Garlic Extracts on Fibrosarcoma in Mice

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2012
BACKGROUND AND OBJECTIVE: Garlic has been shown to have anti-tumoral and anti-metastatic activities in some kinds of cancer. Therefore, it may be effective against fibrosarcoma.
H Shirzad,   +4 more
doaj  

Retrospective histomorphological analysis of bone and soft tissue tumors and tumor-like lesions over 32 years in a tertiary healthcare facility

open access: yesGülhane Tıp Dergisi
Aims: Clinicopathological features of bone and soft tissue tumors/tumor-like lesions have been shown to vary geographically. This study aims to analyze the clinicopathological features of bone and soft tissue lesions in Ilorin, including both neoplastic ...
Mumini Wemimo Rasheed   +6 more
doaj   +1 more source

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