Results 111 to 120 of about 39,976 (222)

Spatiotemporal dynamics of β‐arrestin‐mediated Src activation in 5‐HT7 receptor signaling pathway

open access: yesThe FEBS Journal, Volume 293, Issue 16, Page 5008-5023, August 2026.
GPCRs induce distinct cellular responses via G protein‐ or β‐arrestin‐mediated signaling pathways. This study revealed that β‐arrestin‐biased 5‐HT7R ligand induces slow, sustained Src activation, contrasting with transient G protein‐mediated activation.
Hyunbin Kim   +8 more
wiley   +1 more source

RAS Inhibitor RMC‐7977 Blocks Vascular Overgrowth of NRASQ61R Mutant Endothelial Cells

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT RAS mutations occur in patients with several types of vascular anomalies, but effective treatments remain limited. To address this need, we evaluated the RAS (ON) multi‐selective inhibitor RMC‐7977 in human endothelial cells (ECs) expressing the NRASQ61R mutation found in kaposiform lymphangiomatosis (KLA).
Sara Alharbi   +6 more
wiley   +1 more source

Biomimetic dual-driven STING nanoagonist orchestrates neoadjuvant mild photo-immunotherapy for fibrosarcoma. [PDF]

open access: yesMater Today Bio
Wang Z   +11 more
europepmc   +1 more source

Management of Kaposiform Haemangioendothelioma—A Retrospective Case Series Examining the Use and Effectiveness of Vincristine

open access: yesJournal of Paediatrics and Child Health, Volume 62, Issue 8, Page 1450-1457, August 2026.
ABSTRACT Aim Kaposiform haemangioendothelioma is a rare vascular tumour. Management has evolved over the last two decades, with most cases receiving vincristine or sirolimus. We aim to describe our experience with managing this tumour, with a focus on the safety and efficacy of vincristine.
Bronwen Kirk   +4 more
wiley   +1 more source

Fibrosarcoma Originating in the Tail of a Cat. [PDF]

open access: yesClin Case Rep
Yuki M, Hirano T, Yokota S, Tanabe M.
europepmc   +1 more source

Childhood Ayme-Gripp syndrome: A case report. [PDF]

open access: yesJ Int Med Res
Xu J, Song X, Jia W, Zou C.
europepmc   +1 more source

Juvenile Fibrosarcoma of the Parotid Gland in an Adult Patient: A Case Report. [PDF]

open access: yesCureus
Escobar Howard M   +2 more
europepmc   +1 more source

Recurrence Rates for Mandibular Fibrosarcoma Associated With Mandibular Canal Invasion Following Mandibulectomy Procedures in Dogs. [PDF]

open access: yesVet Comp Oncol
Johnson CP   +11 more
europepmc   +1 more source

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