Results 231 to 240 of about 570,529 (319)

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source

Faculty Opinions recommendation of Local Delivery of miR-21 Stabilizes Fibrous Caps in Vulnerable Atherosclerotic Lesions.

, 2018
Stephen M. Schwartz
openalex   +2 more sources

Osteoprotegerin Promotes Fibrous Cap Formation in Atherosclerotic Lesions of ApoE-Deficient Mice—Brief Report [PDF]

, 2009
О. А. Овчинникова, Åsa Gylfe, Leslie Bailey, Anna Nordström, Mats Rudling, Christian Jung, Sven Bergström, Anders Waldenström, Göran K. Hansson, Peter Nordström   +9 more
openalex   +1 more source

Adducin‐1 Facilitates Influenza Virus Endosomal Trafficking and Uncoating by Regulating Branched Actin Dynamics and Myosin IIB Activity

Advanced Science, EarlyView.
In this study, a novel mechanism is unveiled by which ADD1, acting as a molecular switch, coordinates actin branch dynamics and the transport of endocytic viruses and cargoes. Phosphorylation of ADD1 at Ser726 reduces actin branch density, enhancing endosome fusion and attachment to microtubules.
Meijun Jiang, Jiahui Zou, Yaoming Jin, Chenjun Jiang, Shaoyu Tu, Tong Chen, Jinli Guo, Yanqing Cheng, Meilin Jin, Huanchun Chen, Hongbo Zhou   +10 more
wiley   +1 more source

Manipulation of Oxygen Tension in Damaged Regions via Hypoxia‐Induced IPN Hydrogel Microspheres for Intervertebral Disc Regeneration

Advanced Science, EarlyView.
A novel interpenetrating network hydrogel microsphere (NSC‐Exos@HIMS) is developed to manipulate oxygen tension in damaged regions and recruit endogenous stem cells. In vitro and in vivo results show that NSC‐Exos@HIMS maintains the hypoxia microenvironment for up to 5 days, which triggers nucleus pulposus cell‐like differentiation and enhanced ECM ...
Xingdie Zhou, Zhendong Lv, Zehao Chen, Yiming Xu, Chao Lin, Li Liu, Hao Chen, Bing Niu, Wenguo Cui, Yuhui Zhang   +9 more
wiley   +1 more source

Predicting Endothelium-Dependent Diastolic Function (FMD) and Its Correlation with the Degree of Coronary Artery Disease (CAD) and Plaque Vulnerability for Cardiovascular Events

International Journal of General Medicine
Guangming Zhang,1 Jing Yang,1 Hanghang Xing,1 Hongning Yin,2 Guoqing Gu1 1Department of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050004, People’s Republic of China; 2Department of Heart ultrasound, The Second ...
Zhang G, Yang J, Xing H, Yin H, Gu G
doaj  

Three-Dimensional Fibrous Cap Structure of Coronary Lipid Plaque ― ST-Elevation Myocardial Infarction vs. Stable Angina ―

, 2019
Krzysztof Bryniarski, Zhao Wang, Francesco Fracassi, Tomoyo Sugiyama, Erika Yamamoto, Hang Lee, James G. Fujimoto, Ik–Kyung Jang   +7 more
openalex   +2 more sources

Synergistic Machine Learning Guided Discovery of ABa3(BSe3)2X (A = Rb, Cs; X = Cl, Br, I): A Promising Family as Property‐Balanced IR Functional Materials

Advanced Science, EarlyView.
A synergistic framework for interpretable ML‐assisted target discovery of selenoborates is developed. ABa3(BSe3)2X (A = Rb, Cs; X = Cl, Br, I) are successfully predicted and synthesized, exhibiting significant potential to be promising IR functional materials. This work promotes the cooperation of ML technology and materials science.
Yihan Yun, Mengfan Wu, Zhihua Yang, Guangmao Li, Shilie Pan   +4 more
wiley   +1 more source

Ligand‐Driven Annular‐Epitaxial Growth of CuS‐Au Heterostructures as Trinity Plasmonic Nanozyme for Multimode Diagnosis of Pathogenic Bacteria

Advanced Science, EarlyView.
CuS‐Au heterostructures were synthesized via ligand‐regulated annular‐epitaxial growth strategy, biotin‐Concanavalin A (ConA) was modified on the CuS‐Au heterostructures for universal bacterial‐labelling, assembled with strip, Streptococcus pneumoniae and Klebsiella pneumoniae can be sensitively recognized by SERS/colorimetric/temperature three‐mode ...
Xiaorui Lin, Pengyou Zhou, Miao An, Chenyi Zhu, Yuanfeng Pang, Rui Xiao   +5 more
wiley   +1 more source

Wogonin Attenuates Atherosclerosis via KLF11‐Mediated Suppression of PPARα‐YAP1‐Driven Glycolysis and Enhancement of ABCA1/G1‐Mediated Cholesterol Efflux

Advanced Science, EarlyView.
PPARα promotes KLF11 expression and recruits KLF11 and YAP1 to form a transcription complex, where KLF11 acts as a brake in PPARα‐YAP1‐mediated glycolysis. Wogonin reshapes the metabolism of macrophages from glycolysis to fatty acid oxidation via activation of the PPARα‐KLF11‐YAP1 pathway, by which wogonin reduces inflammation and foam cell formation ...
Chuanrui Ma, Yunqing Hua, Shu Yang, Yun Zhao, Wei Zhang, Yaodong Miao, Jing Zhang, Boxuan Feng, Guobin Zheng, Lan Li, Zhihao Liu, Han Zhang, Mingjun Zhu, Xiumei Gao, Guanwei Fan   +14 more
wiley   +1 more source