Results 111 to 120 of about 298,062 (215)

Endoscopic findings of gallbladder lesions evaluated with image‐enhanced endoscopy: A preliminary study using resected gallbladders

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
Abstract The diagnosis of gallbladder (GB) lesions relies on imaging findings. Transpapillary cholangioscopy can potentially be used to diagnose GB lesions; however, the images obtained remain unclear. This study aimed to characterize the endoscopic findings of GB lesions. We examined the endoscopic features of GB lesions in 50 consecutive patients who
Kiyoyuki Kobayashi   +19 more
wiley   +1 more source

Assessment of Deep Convolutional Neural Network Models for the Classification of Benign Fibro‐Osseous Lesions of the Jaws

open access: yesClinical and Experimental Dental Research, Volume 11, Issue 6, December 2025.
ABSTRACT Objectives Benign fibro‐osseous lesions (BFOL) constitute a group of pathologic entities with marked overlapping histopathologic features but are diverse in nature and clinical behaviors. Accurate diagnoses of BFOLs necessitate clinical‐pathological correlations, which are paramount for their appropriate management.
Paniti Achararit   +5 more
wiley   +1 more source

Neuroaxonal Dystrophy With Osteopetrosis Associated With a Novel Biallelic Nonsense Homozygous Variant in BORCS5

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 11, November 2025.
ABSTRACT Neuroaxonal dystrophy (NAD) with osteopetrosis syndrome (OMIM # 600329) was first reported in a consanguineous Moroccan Jewish family. However, to date, no genetic variant has been linked to this disease. We report on sibs, born to consanguineous Pakistani parents identified prenatally with cerebral ventriculomegaly and agenesis of the corpus ...
Yael Fisher   +6 more
wiley   +1 more source

FIGO good practice recommendations on preconception care: A strategy to prevent preterm birth

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 171, Issue 2, Page 574-587, November 2025.
Abstract Preterm birth (PTB) remains one of the leading causes of neonatal mortality and long‐term morbidity worldwide, with minimal progress being made in reducing its incidence, particularly in low‐resource settings. Preconception care is recognized as an effective strategy for PTB prevention; however, the fact that more than half of pregnancies ...
Leticia Irma Ojeda   +21 more
wiley   +1 more source

Case Report: Association of Ocular Colobomas With a Novel Missense Variant in CDC42, a Member of the Rho Family of Small GTPases

open access: yesClinical Genetics, Volume 108, Issue 5, Page 589-593, November 2025.
We report a 2‐year‐old male with clinical features of Takenouchi‐Kosaki syndrome, bilateral colobomas, and a de novo, likely pathogenic missense variant in CDC42. Supportive evidence includes a Cdc42 conditional knock‐out mouse model with colobomas.
Diana Brightman   +11 more
wiley   +1 more source

Modulation of the Neurovascular Unit by the Locus Coeruleus–Norepinephrine System: From Physiological Mechanisms to Therapeutic Applications

open access: yesThe FASEB Journal, Volume 39, Issue 20, 31 October 2025.
The locus coeruleus (LC)–norepinephrine (NE) system significantly influences the structure and function of the neurovascular unit (NVU). The activation degree and firing patterns of LC–NE neurons, as well as the release amount and action sites of NE, profoundly impact the neurons, glial cells, and cerebrovascular components of the NVU.
Zixin Pan   +7 more
wiley   +1 more source

Role of the Chest Wall in Newborn Respiratory Function at Birth

open access: yesThe FASEB Journal, Volume 39, Issue 19, 15 October 2025.
At birth, liquid is cleared from the airways into lung tissue during lung aeration, causing the lungs to swell, which in turn causes the chest wall to expand. As the newborn chest wall is highly compliant, it can easily expand, but its high compliance reduces breathing efficiency after birth.
C. Diedericks   +8 more
wiley   +1 more source

Systematic Targeting of GD2‐Positive Neuroblastoma Tumors With a Photooncolytic Phage Nanovector Platform

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
A tumor‐penetrating photooncolytic phage is developed for selectively targeting and delivering photosensitizers to GD2‐positive Neuroblastoma cells. Upon light activation, it precisely induces oncolysis of GD2‐positive cells with no effect on GD2‐negative ones.
Suleman Khan Zadran   +25 more
wiley   +1 more source

Deciphering the Acetabular Labrum's Cellular Atlas: MDK Inhibition as a Novel Therapeutic Method for Developmental Dysplasia of the Hip

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
This study explores developmental dysplasia of the hip (DDH) by analyzing acetabular labrum abnormalities using single‐cell and spatial transcriptomics. Aberrant fibrocartilage stem cell proliferation is linked to DDH progression. Targeting the MK signaling pathway with a specific inhibitor effectively alleviates early DDH abnormalities, offering ...
Runze Yang   +10 more
wiley   +1 more source

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