Results 41 to 50 of about 161,435 (256)

Osteosarcoma in a patient with cranial fibrous dysplasia: a case report

Acta Clinica Croatica
Fibrous dysplasia is a benign fibro-osseous lesion which rarely undergoes malignant transformation, frequently after radiotherapy. Osteosarcoma is the most common malignancy arising in fibrous dysplasia.
Danko Müller, Naranđa Aljinović Ratković, Igor Blivajs, Dalibor Franćeski, Karolina Krstanac, Sven Seiwerth   +5 more
doaj   +1 more source

Chromosome aberations in fibrous dysplasia

, 1994
We report the cytogenetic findings of two cases of fibrous dysplasia, one occurring in the tibia, the other in the sphenoid. Both cases exhibited only one chromosome change: a t(6;11)(q15;p15) in the first case, a derivative chromosome 2 in the second ...
Speleman, Franki, Raf Sciot, De Potter, C, Christian De Potter, Paola Dal Cin, Laureys, Genevieve, Geneviève Laureys, Sciot, R, Dalcin, P, Frank Speleman, Meire, Françoise, Van Damme, B, Ignace Samson, Herman Van Den Berghe, Van Den Berghe, H, Françoise Meire, Samson, I, Boudewijn Van Damme   +17 more
core   +1 more source

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source

MALIGNANT CHANGE IN FIBROUS DYSPLASIA

, 1964
A brief review of the literature on malignant change occurring in fibrous dysplasia is given and a further case of a sarcoma arising in a patient with polyostotic fibrous dysplasia is reported.
D. M. Riddell
core   +1 more source

A rhesus macaque model of α‐dystroglycanopathy caused by a POMT1 splice altering variant

Animal Models and Experimental Medicine, EarlyView.
Rhesus macaques homozygous for a naturally occurring spice altering variant in the POMT1 gene develop lissencephaly, microphthalmia, and muscular contracture. The presentation models severe presentation of the human Walker‐Warburg syndrome. Abstract Background Biallelic mutations in genes associated with α‐dystroglycan glycosylation manifest in a ...
Anya Nordlund, Brian LaMendola, Nathan P. Crilly, Seth Kittle, Betsy M. Ferguson, Anne D. Lewis, Jeff Wall, Samuel M. Peterson   +7 more
wiley   +1 more source

Protein kinase A is a dependent factor and therapeutic target in mouse models of fibrous dysplasia

Nature Communications
Fibrous dysplasia is a skeletal disorder caused by activating mutations in Gαs, leading to bone fractures, deformities, and pain. Protein kinase A (PKA), the principal effector of Gαs, plays critical roles in various biological processes.
Zhongyu Liu, Lu Xing, Wenlong Huang, Ning Ji, Hang Zhao, Qianming Chen, Xianglong Han, Ding Bai, Xuefeng Zhao   +8 more
doaj   +1 more source

Tibial fibrous dysplasia in children treated by Ilizarov technique – a review of treatment options

Гений oртопедии, 2021
Fibrous dysplasia is a pathological condition, where normal medullary bone is replaced by fibrous tissue and small woven specules of bone. Fibrous dysplasia can occur in epiphysis, metaphysis or diaphysis.
Mofakhkharul M. Bari, Islam Shahidul, Ashraf Tanvir, A.M. Shayan R. Bari   +3 more
doaj   +1 more source

Displasia fibrosa dos ossos da face e do crânio: revisão da literatura e relato de três novos casos. [PDF]

, 1999
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Cirúrgica, Curso de Medicina, Florianópolis ...
Casagrande, Maika Adriana Dione
core  

Aortic valve disease: Novel animal models for advancing our understanding of the underlying mechanisms

Animal Models and Experimental Medicine, EarlyView.
Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Liya Hou, Xue Liu, Wangxing Hu, Xianbao Liu, Wei Zhu   +4 more
wiley   +1 more source

Bilateral fibrous dysplasia of the mandible in a 7-year-old male patient-A rare case

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2010
Fibrous dysplasia is a disturbance of bone metabolism that is classified as a benign fibro-osseous lesion. Fibrous connective tissue, containing abnormal bone, replaces normal bone. The etiology of fibrous dysplasia is unknown.
Chandar V, Priya, Amita
doaj