Results 111 to 120 of about 633,082 (292)
Neotectonic study of Northwestern Greece
Journal of Maps, 2018 In this paper, a neotectonic map with active faults, at a scale of 1:500,000, of the northwestern Greece is presented and discussed. The elaboration of the Neotectonic Map chiefly aimed at the identification, mapping and assessment of the faults in the ...
Dimitrios Ntokos
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Co-Concept Analysis in Bioinformatics Field by Yewno Based on Experts’ Viewpoints
International Journal of Information Science and Management, 2020 In this paper, the opinions of bioinformatics experts were sought to examine the knowledge semantic maps. The research question was whether the mapping of bioinformatics field articles could contribute to the reflection of knowledge map in this field ...
Masoume Kiani +3 more
doaj
B1 field map synthesis with generative deep learning used in the design of parallel-transmit RF pulses for ultra-high field MRI. [PDF]
Z Med Phys, 2022 Eberhardt B +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Gray Images of Constacyclic Codes Over Some Polynomial Residue Rings
پژوهشهای ریاضی, 2021 Let be the quotient ring where is the finite field of size and is a positive integer. A Gray map of length over is a special map from to ( .
Reza Sobhani
doaj
Simultaneous changes in visual acuity, cortical population receptive field size, visual field map size, and retinal thickness in healthy human aging. [PDF]
Brain Struct Funct, 2021 Silva MF +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source