Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang +12 more
wiley +1 more source
Applications and Future Prospects of Plant Multi-Omics Technologies in Precision Agriculture. [PDF]
Tong T +7 more
europepmc +1 more source
Descriptor‐Informed Screening of Interface‐Active Molecules for Efficient Magnesium Metal Anodes
A descriptor‐informed molecular screening strategy identifies 4‐bromo‐N, N‐dimethylaniline (BrNNA) as an interface‐active electrolyte component that enables fast Mg stripping/plating in Mg(TFSI)2‐based electrolytes. By simultaneously regulating Mg2+ solvation and interphase formation, the BrNNA‐containing electrolyte delivers activation‐free Mg ...
Hao Xu +16 more
wiley +1 more source
Unlocking associative nitrogen fixation in Poaceae: molecular mechanisms, regulatory constraints, and pathways to sustainable productivity. [PDF]
Nong Q +8 more
europepmc +1 more source
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol +16 more
wiley +1 more source
Crop-associated differentiation of rhizosphere microbial communities and soil functional traits in saline-alkaline farmland. [PDF]
Zhang X +7 more
europepmc +1 more source
Charge Storage and Dark Photocatalysis in Multivariate Ti‐Based Metal‐Organic Frameworks
The mixed‐linker series of the titanium‐based metal–organic framework COK‐47 enables systematic tuning of photoresponsiveness and (dark) photocatalytic activity, deepening our understanding of structure‐property‐function relationships. Tailored metal‐to‐ligand charge transfer between the secondary building units (metal‐oxo layers and organic linkers ...
Julia E. Knapp +11 more
wiley +1 more source
Biochar-mediated uptake of secondary- and micro-nutrients in crops: a meta-analysis. [PDF]
Yuan M +7 more
europepmc +1 more source
Donor–acceptor molecular design and chemical vapor deposition growth enable the two‐dimensional nickel‐tetraaminobenzoquinone films with strong broadband absorption and efficient charge separation. The resulting photodetectors exhibit a structured broadband response with a high responsivity of ∼3.1 A W−1 and a response time of ∼170 µs, which surpasses ...
Yunxu Chen +14 more
wiley +1 more source
Integrating Land-Cover Dynamics and Management Records for Recovery Monitoring of Hainan Eld's Deer in Datian National Nature Reserve. [PDF]
Chen T +5 more
europepmc +1 more source

