Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Drought effect on maize seedling development [PDF]
Ratarstvo i Povrtarstvo, 2018 Drought stress is one of the most important abiotic stresses influencing performance of crops. Certain stress-related conditions can appear and slow down germination, seedling development and in some cases cause loss of life durability of seed.
Radić Velimir +5 more
doaj
Genetic resources of alternative crops [PDF]
Selekcija i Semenarstvo, 2017 Alternative crops are known as plant species that occupy small and variable agricultural areas. The crops adapted to agro ecological conditions of Southeast Europe are with the developed technology of the production which means machinery commonly used ...
Sikora Vladimir +5 more
doaj +1 more source
The efficiency of a durum wheat-winter pea intercrop to improve yield and wheat grain protein concentration depends on N availability during early growth [PDF]
, 2010 Grain protein concentration of durum wheat is often too low, particularly in low-N-input systems. The aim of our study was to test whether a durum wheat - winter pea intercrop can improve relative yield and durum wheat grain protein concentration in low ...
Bedoussac, Laurent, Justes, Eric
core
Unraveling Field Crops Sensitivity to Heat Stress：Mechanisms, Approaches, and Future Prospects
Agronomy, 2018 The astonishing increase in temperature presents an alarming threat to crop production worldwide. As evident by huge yield decline in various crops, the escalating drastic impacts of heat stress (HS) are putting global food production as well as ...
M. Nadeem +6 more
semanticscholar +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
GGE biplot analysis of sugar beet multi-environment trials [PDF]
Ratarstvo i Povrtarstvo, 2017 Multi-environment trials are performed every year with the aim of evaluating sugar beet varieties in different environmental conditions of Serbia.
Ćurčić Živko +5 more
doaj +1 more source
Field emissions of N2O during biomass production may affect the sustainability of agro-biofuels [PDF]
, 2011 Field emissions of N2O during cultivation of bioenergy crops may counterbalance a considerable part of the avoided fossil CO2 emissions that are achieved by fossil fuel ...
Ambus, Per +7 more
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Variation in NDVI values and relationship with grain yield in two-rowed winter barley [PDF]
Ratarstvo i Povrtarstvo, 2018 The simple methods used for indirect biomass determination are recognized as potentially important tools for crop growth prediction. The normalized difference vegetation index (NDVI) is widely used for assessing crop biomass, yield, photosynthesis, and ...
Mirosavljević Milan +5 more
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