Results 51 to 60 of about 8,354,979 (301)

Observations and modelling of birch pollen emission and dispersion from an isolated source [PDF]

open access: yes, 2014
The occurrence of allergic diseases in western countries increased during the last decades due to greater awareness towards a hygienic lifestyle. The hygiene hypothesis relates the reduced expo- sure to microbial pollution to an underdevelopment of the
Michel, Dominik
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Stable Field Emission from Layered MoS2 Nanosheets in High Vacuum and Observation of 1/f Noise [PDF]

open access: yes, 2015
Field emission and current noise of hydrothermally synthesized MoS2 nanosheets are investigated in ultra- high-vacuum and industrially suited high-vacuum conditions. The study reveals that the emission turn-on field is pressure dependent.
Mahendra A. More   +11 more
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Direct observation of sub-threshold field emission from silicon nanomembranes

open access: yes, 2011
Excited by an energetic electron beam, field enhanced electron emission from a silicon nanomembrane is examined by using a local current probe. The experiments reveal clear transitions from conventional secondary electron emission (SEE) to sub-threshold ...
Tan, RB (谭仁兵)   +9 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

A Novel, Hybrid-Integrated, High-Precision, Vacuum Microelectronic Accelerometer with Nano-Field Emission Tips

open access: yesMicromachines, 2018
In this paper, a novel, hybrid-integrated, high-precision, vacuum microelectronic accelerometer is put forward, based on the theory of field emission; the accelerometer consists of a sensitive structure and an ASIC interface (application-specific ...
Haitao Liu   +5 more
doaj   +1 more source

MitigatePlus: Research for low-emission food systems

open access: yes, 2023
MitigatePlus: Research for Low-Emission Food Systems is one of the Research Initiatives in CGIAR’s new research portfolio that will deliver science and innovation to transform food, land, and water systems in a climate crisis.
Verchot, Louis; Zhang, Wei   +1 more
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Development of Crystalline Cu2S Nanowires via a Direct Synthesis Process and Its Potential Applications

open access: yesNanomaterials, 2020
Large-scale and uniform copper(I) sulfide (Cu2S) nanowires have been successfully synthesized via a cheap, fast, easily handled, and environmentally friendly approach.
Chih-Yen Chen   +4 more
doaj   +1 more source

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