Results 111 to 120 of about 2,215,078 (318)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

The Development of Field Artillery Material [PDF]

Royal United Services Institution. Journal, 1891
(1891). The Development of Field Artillery Material. Royal United Services Institution. Journal: Vol. 35, No. 158, pp. 321-344.
openaire   +1 more source

Dielectric polarization in inverse spinel‐structured Mg2TiO4 coating to suppress oxygen evolution of Li‐rich cathode materials

, 2020
High‐energy Li‐rich layered cathode materials (≈900 Wh kg−1) suffer from severe capacity and voltage decay during cycling, which is associated with layered‐to‐spinel phase transition and oxygen redox reaction.
Huarong Xia, Anmin Cao, Yonggang Sun, Huiqiu Deng, Jianming Ma, Zhisheng Lv, Du, Yonghua, Xiang Ge, Chen, Xiaodong, Yi Zeng, Zhu, Zhiqiang, Ma, Jianming, Zeng, Yi, Cao, Shengkai, Cao, Anmin, Yonghua Du, Wei Zhang, Yao Xiao, Zhang, Wei, Sun, Yonggang, Xia, Huarong, Shengkai Cao, Xi, Shibo, Xiaodong Chen, Deng, Huiqiu, Lv, Zhisheng, Xiao, Yao, Zhiqiang Zhu, Shibo Xi, Ge, Xiang   +29 more
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Failure Case Study Series Part Four: Investigation of the Failure Mechanism of the Connecting Rod in an Industrial Oxygen Compressor

The Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science
This investigation addresses the catastrophic fracture of a connecting rod in an oxygen compressor unit during steady‑state operation. Owing to its function in transmitting cyclic compressive and tensile loads between the crankshaft and the piston, the ...
Liviu GURĂU, Florin MARIN, Mihaela MARIN, Cristian ȘTEFĂNESCU, Gheorghe GURĂU   +4 more
doaj   +1 more source

Exciton diamagnetic shifts and valley Zeeman effects in monolayer WS2 and MoS2 to 65 Tesla

Nature Communications, 2016
The spin and valley degrees of freedom are coupled in two-dimensional transition-metal dichalcogenides. Here, the authors use high magnetic fields to optically measure the valley Zeeman effect and diamagnetic exciton shift in tungsten disulphide and ...
Andreas V. Stier, Kathleen M. McCreary, Berend T. Jonker, Junichiro Kono, Scott A. Crooker   +4 more
doaj   +1 more source

Electrooptic electric field sensor for dc and extra-low-frequency measurement

, 1998
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The thesis reports the results of the research carried out towards the development of an electrooptic sensor for DC and extra low frequency electric field ...
Bordovsky, Michael
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

An atomically controlled insulator-to-metal transition in iridate/manganite heterostructures

Nature Communications
All-insulator heterostructures with an emerging metallicity are at the forefront of material science, which typically contain at least one band insulator while it is not necessary to be.
Enyang Men, Deyang Li, Haiyang Zhang, Jingxin Chen, Zhihan Qiao, Long Wei, Zhaosheng Wang, Chuanying Xi, Dongsheng Song, Yuhan Li, Hyoungjeen Jeen, Kai Chen, Hong Zhu, Lin Hao   +13 more
doaj   +1 more source