Results 111 to 120 of about 9,410,111 (262)

Can Chemoradiotherapy Expand Immune Checkpoint Blockade Responsiveness in Mismatch Repair‐Proficient Rectal Cancer? [PDF]

Ann Gastroenterol Surg
ABSTRACT Immune checkpoint blockade (ICB) has transformed the treatment of mismatch repair‐deficient (dMMR) colorectal cancer but produces no meaningful benefit in advanced mismatch repair‐proficient (pMMR) disease. In the neoadjuvant setting, however, pathological responses have been reported in a subset of pMMR tumors, suggesting that clinical ...
Yamashita K, Matsuda T, Mukohyama J, Sasaki R, Kakeji Y.   +4 more
europepmc   +2 more sources

Longitudinal Awake Mouse Brain Imaging Using Functional Ultrasound and Functional Ultrasound Localization Microscopy

Advanced Science, EarlyView.
Awake longitudinal multimodal ultrasound imaging integrates functional ultrasound (fUS), ultrasound localization microscopy (ULM), and functional ULM (fULM) to characterize cerebrovascular function, microvascular architecture, and flow dynamics within the same animals over time.
Zhe Huang, Yike Wang, Matthew R. Lowerison, Yue Xu, Murong Yi, Bing‐Ze Lin, YiRang Shin, Nathiya Vaithiyalingam Chandra Sekaran, Daniel A. Llano, Pengfei Song   +9 more
wiley   +1 more source

Comparative studies on progeny test results from stations and field data [PDF]

Genetics Selection Evolution, 1971
openaire   +4 more sources

Explaining the Origin of Negative Poisson's Ratio in Amorphous Networks With Machine Learning

Advanced Intelligent Discovery, EarlyView.
This review summarizes how machine learning (ML) breaks the “vicious cycle” in designing auxetic amorphous networks. By transitioning from traditional “black‐box” optimization to an interpretable “AI‐Physics” closed‐loop paradigm, ML is shown to not only discover highly optimized structures—such as all‐convex polygon networks—but also unveil hidden ...
Shengyu Lu, Xiangying Shen
wiley   +1 more source

Expectation and variance of genetic gain in open and closed nucleus and progeny testing schemes

, 1991
Open and closed nucleus and conventional and modern progeny testing schemes were compared for expectation and variance of genetic gain. Generation intervals were optimized, with minimum values of 2 and 6 years (progeny test results available) for males ...
T. H. E. Meuwissen
core   +1 more source

Seeds of change: The impact of Ethiopia's direct seed marketing approach on smallholders' seed purchases and productivity

American Journal of Agricultural Economics, EarlyView.
Abstract While multiple factors explain low adoption rates of improved varieties by small‐scale farmers in sub‐Saharan Africa, a key supply‐side constraint is the limited availability of seed embodying new traits in the volume, quality, price, and timeliness required by farmers. This constraint is partly attributable to classical failures in the market
Dawit Mekonnen, Gashaw T. Abate, Seid Yimam, Rui Benfica, David J. Spielman, Frank Place   +5 more
wiley   +1 more source

Growth ranking of hybrid aspen genotypes and its linkage to leaf gas exchange

BMC Plant Biology
Background Afforestation of non-forestland is a new measure by the European Union to enhance climate mitigation and biodiversity. Hybrid aspen (Populus tremula L. × P.
Ott Kangur, Reeno Sopp, Arvo Tullus, Priit Kupper, Eele Õunapuu-Pikas, Hardi Tullus, Reimo Lutter   +6 more
doaj   +1 more source

Principles for regulatory testing and interpretation of semi-field and field studies with non-target arthropods

, 2000
This paper is a guidance document for side-effect testing with plant protection products on non-target arthropods under semi-field and field conditions.
Campbell, P., Angeli, G., Pasqualini, E., Schmuck, R., Carli, G., Dinter, A., Vergnet, C., Hassan, S., Neumann, P., Thieme, Angeli, Gino, Forster, R., Forti, D., Vogt, H., Candolfi, M., Reboulet, J. N., Forti, Diego, Bakker, F., Mead Briggs, M., Melandri, M., Reboulet, J-N., Powell, W., Ufer, A., Thieme, T., Mead-Briggs, M., Neuwmann, P., Romijn, K., Heimbach, U., Vergnet, Ch., Gathmann, A., Sechser, B., Bigler, F., Brown, K.   +32 more
core   +1 more source

Interactions between maternal provisioning and natural selection on seed mass fluctuate across heat waves

American Journal of Botany, EarlyView.
Abstract Premise Changing climates are leading to more frequent and severe heat waves, potentially threatening plant populations. Both acclimation to stress and selection for heat‐escape or heat‐resistance phenotypes occur during heat waves. However, plastic responses and selection do not necessarily interact cohesively—even producing trait responses ...
Lana F. Gaspard, Elissa Harb, Stacy D. Holt Jr., Courtney M. Patterson, Nicholas J. Kooyers   +4 more
wiley   +1 more source

A Novel Constitutional TUBB Variant Associated With Familial Malformations of Cortical Development

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Most pathogenic tubulin variants arise de novo in sporadic patients, causing severe brain malformations and significant neurodevelopmental impairment. The resulting reproductive disadvantage typically prevents these mutations from being transmitted to offspring.
Elena Cellini, Davide Mei, Mara Cavallin, Simona Fiori, Luciana Tramacere, Maria Elena Melica, Giulia Antonelli, Simona Virdò, Elena Parrini, Renzo Guerrini   +9 more
wiley   +1 more source