Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
[Topographic survey of India & surrounding countries 1:63 360] [cartographic material].
Various eds. Topographic map series of British India (now India, Pakistan, Bangladesh, Nepal, Bhutan and Burma) showing roads, railways, tracks, bridges, rest houses, spaced names, dams, light houses, grass lands, cliffs, graves, water features, foot ...
Survey of India.
core
Well-Being and Healthcare Inequality on Bulon-Don Island in Southern Thailand-Results of a Pre-Intervention Field Survey. [PDF]
Sathirapanya C +2 more
europepmc +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Training, practice, and career considerations in forensic psychology: results from a field survey of clinical and non-clinical professionals in the United States. [PDF]
LaDuke C +3 more
europepmc +1 more source
The Cover Depth Effect on Corrosion-Induced Deterioration of Reinforced Concrete Focusing on Water Penetration: Field Survey and Laboratory Study. [PDF]
Asamoto S +5 more
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Field survey of reproductive modes and sodium channel mutations associated with pyrethroid resistance in Thrips tabaci. [PDF]
Tomizawa Y +3 more
europepmc +1 more source
Association between Internet Addiction and Application Usage among Junior High School Students: A Field Survey. [PDF]
Kawabe K +4 more
europepmc +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source

