Results 121 to 130 of about 7,278,095 (302)
Field Measurements of Spontaneous Potential (SP) for Smart Well Monitoring and Control. A Field Test in the UK Chalk Aquifer [PDF]
Imperial Users ...
Esquivel Garcia, Armando +1 more
core
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Simulation Analysis and Field Test of Torque Impact Drilling Tool
To address the stick-slip effect of PDC bit during drilling, a torque impact drilling tool was developed based on the principle of circumferential vibration of hydraulic structure.
Chen Xinyong +5 more
doaj
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Testing visual fields using "two" fingers; one eye occluded with patient hand, testing one quadrant at a time https://ir.lib.uwo.ca/clinicalskills_neuroexam/1529/thumbnail ...
openaire +3 more sources
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Design and Experimental Results Obtained with an Astragalus Digger Prototype
Traditional methods for harvesting medicinal materials with long roots, like Astragalus membranaceus, require extensive soil excavation, leading to problems like inefficient soil separation, low stemming rates, and blockages in conveyor chains.
Jianpu Du +4 more
doaj +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source

