KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Acceptability and Feasibility of a Prototype Regional Disaster Teleconsultation System for COVID-19 Pandemic Response: Pilot Field Test. [PDF]
Ludy S +7 more
europepmc +1 more source
A systematic review and meta-analysis of thigmotactic behaviour in the open field test in rodent models associated with persistent pain. [PDF]
Zhang XY +13 more
europepmc +1 more source
The role of lipid metabolism in neuronal senescence
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Development and field test of the child and adolescent sleep checklist for parents of community junior high school students. [PDF]
Kawabe K +6 more
europepmc +1 more source
First Field Test of the Novel Integration Mapping Tool for COVID-19 Vaccination Integration into National Immunization Programs and Primary Healthcare-A Case Study from Côte d'Ivoire. [PDF]
Amani A +13 more
europepmc +1 more source
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Field Test of a Bioelectrochemical Membrane-Less Reactor for Chlorinated Aliphatic Hydrocarbon and Nitrate Removal from a Contaminated Groundwater. [PDF]
Sassetto G +6 more
europepmc +1 more source
Functional Threshold Power Field Test Exceeds Laboratory Performance in Junior Road Cyclists. [PDF]
Vinetti G +8 more
europepmc +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source

