Results 91 to 100 of about 719,802 (285)

Critical exponents from optimised renormalisation group flows [PDF]

open access: yes, 2002
Within the exact renormalisation group, the scaling solutions for O(N) symmetric scalar field theories are studied to leading order in the derivative expansion. The Gaussian fixed point is examined for d>2 dimensions and arbitrary infrared regularisation.
Aoki   +47 more
core   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

E 8 instantons on type-A ALE spaces and supersymmetric field theories

open access: yesJournal of High Energy Physics, 2017
We consider the 6d superconformal field theory realized on M5-branes probing the E 8 end-of-the-world brane on the deformed and resolved ℂ 2/ℤ k singularity.
Noppadol Mekareeya   +3 more
doaj   +1 more source

Abelian-Projected Effective Gauge Theory of QCD with Asymptotic Freedom and Quark Confinement [PDF]

open access: yes, 1997
Starting from SU(2) Yang-Mills theory in 3+1 dimensions, we prove that the abelian-projected effective gauge theories are written in terms of the maximal abelian gauge field and the dual abelian gauge field interacting with monopole current.
A. Hart   +65 more
core   +3 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Discrete gauging in six dimensions

open access: yesJournal of High Energy Physics, 2018
When n M5 branes coincide on an A type singularity, ℂ2 /ℤ k , there is a multitude of tensionless strings which arise in the spectrum. The low energy theory when all M5 branes are separated at the singularity is given by a linear quiver with parameters n
Amihay Hanany, Gabi Zafrir
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Computing Yukawa Couplings from Magnetized Extra Dimensions

open access: yes, 2004
We compute Yukawa couplings involving chiral matter fields in toroidal compactifications of higher dimensional super-Yang-Mills theory with magnetic fluxes. Specifically we focus on toroidal compactifications of D=10 super-Yang-Mills theory, which may be
  +56 more
core   +1 more source

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