Results 131 to 140 of about 693,380 (314)
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods
A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators +26 morewiley +1 more sourceFeasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background
Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method
This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen +19 morewiley +1 more sourceScHAL1-Mediated Enhancement of Salt Tolerance in Soybean: From Stable Transgenic Inheritance to Field Trial Validation. [PDF]
Plant Biotechnol JYu Z, Wei J, Cai Q, Zhang Y, Zhao Q, Niu L, Ren P, Shang L, Yang X, Dong Y, Ma R. +10 moreeuropepmc +1 more sourceField Trials to Evaluate Five Fasciolicides against Natural Liver Fluke Infection in Cattle and Sheep in Egypt
, 2022 Walaa Mostafa, Ahmed Abdel-Rady, Mohamed Eldakroury, Wael Felefel, S Aghayan, H Gevorgian, D Ebi, H Atoyan, F Addy, U Mackenstedt, T Romig, M Wassermann, M Alsulami, Mohamed, M Alvarez-Sanchez, R Mainar-Jaime, J Perez-Garcia, Rojo-Vzquez F, M Asrat, E Bazh, N Beder, M Ayoub, K Sadek, J Boray, P Crowfoot, M Strong, J Allison, M Schellenbaum, Von Orelli, M Sarasin, G, J Charlier, S Bennema, Y Caron, M Counotte, E Ducheyne, G Hendrickx, J Vercruysse, G Coles, F Curtalei, E Hammoudz, El Wakeel, A Mas-Coma, S Savioli, L, B Elitok, Elitok, M Kabu, A Elkhtam, R Khalafalla, N Elshraway, Mahmoud, A El-Tahawy, E Bazh, R Khalafalla, M Gebreyohannes, Y Demeke, E Kebede, S George, A George, Rolfe Emery, D, F Happich, J Boray, F Haridy, T Morsy, N Gawish, Antonios Tn, Abdel Gawad, A, M Karim, Mahmud Ms, M Giasuddin, J Keyyu, A Kassuku, N Kyvsgaard, J Monrad, S Khademvatan, H Majidiani, H Khalkhali, A Taghipour, N Asadi, E Yousefi, C Kipyegen, C Muleke, E Otachi, B Kuerpick, F Conraths, C Staubach, A Froehlich, T Schnieder, C Strube, Fms Maha, L Marcos, P Yi, A Machicado, R Andrade, F Samalvides, J Snchez, A Terashima +99 moreopenalex +1 more sourceStructure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives
Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese +11 morewiley +1 more sourceProtocol for a Pre-Post Field Trial of a Home Hearing and Vision Care Program for Older Australians With Diverse Cognitive Abilities and Hearing and/or Vision Impairment. [PDF]
Health Sci RepToomey M, Gurteen H, Bennett B, Cenin D, El-Saifi N, Ferguson M, Gu Y, Heine C, Keay L, Kumaran S, Lenzen S, Leroi I, Lowthian JA, Meyer C, Mitchell L, Newall J, Pachana NA, Piano M, Raichand S, Scanlan E, Sohrabi HR, Dawes P. +21 moreeuropepmc +1 more sourceComplementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh +17 morewiley +1 more source