Results 121 to 130 of about 2,725,591 (316)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
A keen collector and sketcher of plant specimens from an early age, the author, educator and clergyman Charles Alexander Johns (1811–74) gained recognition for his popular books on British plants, trees, birds and countryside walks. The Forest Trees of Britain (1847–9), one of several works originally published by the Society for Promoting Christian ...
openaire +7 more sources
Fields of The World: A Field Guide for Extracting Agricultural Field Boundaries
CoRRField boundary maps are a building block for agricultural data products and support crop monitoring, yield estimation, and disease estimation. This tutorial presents the Fields of The World (FTW) ecosystem: a benchmark of 1.6M field polygons across 24 countries, pre-trained segmentation models, and command-line inference tools. We provide two notebooks
Isaac Corley +3 more
openaire +2 more sources
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Technological development in Therapeutic applications of alternating electric fields: Review
, 2012 A number of bacteria, virus and other unhealthy cells need to be killed for getting rid of them. For more than a century antibiotics have been effectively used for killing bacterial pathogens and chemical drugs against the cancer cells.
Talele, Sadhana
core
Reconfigurable artificial neuron and synapse enabled through a single alloyed memristor
Scientific ReportsMemristive devices have drawn significant interest due to their use in novel paradigms such as neuromorphic computing. Neuromorphic systems are developed by implementing artificial neurons and synapses on a hardware level.
Elias Passerini +13 more
doaj +1 more source
Caderno CRHA sociologia dos mercados tem sido um dos campos mais vibrantes da sociologia nos últimos 25 anos. Há uma boa dose de concordância de que os mercados são estruturas sociais caracterizadas por relações sociais extensas entre firmas, trabalhadores ...
Neil Fligstein, Luke Dauter
doaj +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source