Results 231 to 240 of about 3,416,587 (304)

Founding Editorial: Neuro‐Drug Discovery

Neuro-Drug Discovery, EarlyView.
Wenbin Li
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Robust enhanced leaf model implementation for beam-matched linear accelerators: Impact of physical leaf gap variations. [PDF]

J Appl Clin Med Phys
Lee S, Galavis PE, Jang S.
europepmc   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Oral Health Status And Oral Health Related Quality of Life in Children With Congenital Heart Disease-A Systematic Review And Meta-Analysis. [PDF]

Spec Care Dentist
Sharma A, Saxena A, Goswami M, Singhal P, Phukan MK, Karak S, Soni Y.   +6 more
europepmc   +1 more source

On the Genus Fields of Pure Number Fields

Tokyo Journal of Mathematics, 1980
openaire   +2 more sources

Shaping Nematic Liquid Crystal Flow States with In-Plane Electric Fields. [PDF]

Materials (Basel)
Emeršič T, Tkalec U.
europepmc   +1 more source

Nanofabrication of Topological Surface Relief Structures in Azopolymers With Tightly Focused Optical Skyrmions. [PDF]

Nanophotonics
Omatsu T, Hirayama S, Reddy ANK, Okida M, Taguchi A.   +4 more
europepmc   +1 more source

Corrigendum to "Matrix nanoalignment programs macrophage vesicular immunity through TRPV2 mechanogating" [Bioact. Mater. 69 (2027) 18-32]. [PDF]

Bioact Mater
Yin B, Xiang G, Zhang Z, Zheng L, Wang R, Zhang Q, Huang Y, Liu C, Chi J, Xia X, Yan J, Wang J, Yang M, Bian L, Wong SHD.   +14 more
europepmc   +1 more source