Results 21 to 30 of about 230,200 (216)

Single‐Cell Analysis Clarifies Pathological Heterogeneity in Tenosynovial Giant Cell Tumor and Identifies Biomarkers for Predicting Disease Recurrence

open access: yesAdvanced Science, EarlyView.
MP3 tumor cells, a specific subpopulation of tumor cells in D‐TGCT, regulated the differentiation of CD34+ Fbs into MMP3+ Fbs and APOE+ Fbs through COL6A3 − (ITGAV + ITGB8) interaction. APOE+ Fbs activated IL‐1B+CCL20+ Mφs through the CXCL12/CXCR4 axis. IL‐1B+CCL20+ Mφs and MMP3+ Fbs participated in the local invasion of D‐TGCT.
Yubin Xie   +15 more
wiley   +1 more source

MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang   +9 more
wiley   +1 more source

Early exposure to flame retardants is prospectively associated with anxiety symptoms in adolescents: A prospective birth cohort study

open access: yesDepression and Anxiety, Volume 39, Issue 12, Page 780-793, December 2022., 2022
Abstract Background Anxiety disorders emerge during childhood and adolescence and are frequently preceded by subsyndromal anxiety symptoms. Environmental toxicants, including gestational polybrominated diphenyl ether (PBDE) exposure, are associated with neuropsychiatric sequelae; however, the role of PBDEs as risk factors for anxiety in adolescence is ...
Jeffrey R. Strawn   +9 more
wiley   +1 more source

Bioinspired Liquid‐Free Ion‐Conductive Elastomers with Ultrahigh Mechanical Strength and Excellent Ionic Conductivity for Multifunctional Flexible Sensing Applications

open access: yesAdvanced Science, EarlyView.
⁻Inspired by the “brick wall” structure of pearl layer, FLICE‐110% liquid‐free ionic conductive elastomer had high mechanical strength (5.46 MPa), excellent ionic conductivity (3.29 × 10−4 S cm−1) and resilience. It can be used in smart music boxes, airplane wings and control manipulators.
Zequan Li   +13 more
wiley   +1 more source

Real‐time assessment of positive and negative affective fluctuations and mood lability in a transdiagnostic sample of youth

open access: yesDepression and Anxiety, Volume 39, Issue 12, Page 870-880, December 2022., 2022
Abstract Background Emotional lability, defined as rapid and/or intense affect fluctuations, is associated with pediatric psychopathology. Although numerous studies have examined labile mood in clinical groups, few studies have used real‐time assessments in a well‐characterized transdiagnostic sample, and no prior study has included participants with ...
Reut Naim   +5 more
wiley   +1 more source

Towards Neural Functional Program Evaluation [PDF]

open access: yesarXiv, 2021
This paper explores the capabilities of current transformer-based language models for program evaluation of simple functional programming languages. We introduce a new program generation mechanism that allows control over syntactic sugar for semantically equivalent programs.
arxiv  

US employment exposure to domestic and foreign tariff changes under NAFTA

open access: yesApplied Economic Perspectives and Policy, EarlyView.
Abstract Literature examining the effects of changes in trade agreements and import competition on US employment and wages has focused primarily on non‐agricultural industries and changes in US import tariffs. We propose a method for measuring worker exposure to changes in agricultural tariffs using a newly developed county‐level dataset of employment ...
Diane E. Charlton   +3 more
wiley   +1 more source

Reciprocal relationships between personality disorders and eating disorders in a prospective 17‐year follow‐up study

open access: yesInternational Journal of Eating Disorders, Volume 55, Issue 12, Page 1753-1764, December 2022., 2022
Abstract Objective This study aimed to report the presence of categorical and dimensional personality disorders (PD) in adults with longstanding eating disorders (ED) over a period of 17 years and to investigate whether changes in PD predict changes in ED symptoms or vice versa.
Hanna Punsvik Eielsen   +4 more
wiley   +1 more source

What matters for agricultural trade? Assessing the role of trade deal provisions using machine learning

open access: yesApplied Economic Perspectives and Policy, EarlyView.
Abstract This paper employs machine learning to determine which preferential trade agreement (PTA) provisions are relevant to agricultural trade patterns and the factors that may influence their adoption. Utilizing the three‐way gravity model, we apply plug‐in Lasso regularized regression to pinpoint predictive PTA provisions for agricultural trade ...
Stepan Gordeev   +3 more
wiley   +1 more source

Magnetic Skin for Voice Disorders with Real‐Time Lip Translation

open access: yesAdvanced Intelligent Systems, EarlyView.
Soüti, a novel wearable technology combining flexible, biocompatible magnetic skin patches with a convolutional neural network to translate lip movements into speech with 92.54% accuracy. This innovative approach enhances therapeutic options for speech impairments and democratizes access to advanced healthcare technologies, particularly benefiting ...
Montserrat Ramirez‐De Angel   +6 more
wiley   +1 more source

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