Results 231 to 240 of about 85,792 (305)

Is Thymic Involution Truly a Deterioration or an Adaptation? [PDF]

Bull Math Biol
Iwasa Y, Hayashi R, Hara A, Matsuo K.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Jumping Kinematics and Performance in Fighting Crickets Velarifictorus micado. [PDF]

Biomimetics (Basel)
Xing Y, Zhang Y, Yan Y, Yang J.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Review of Advances in Fire Extinguishing Based on Computer Vision Applications: Methods, Challenges, and Future Directions. [PDF]

Sensors (Basel)
Loboichenko V, Wilk-Jakubowski G, Pawlik L, Wilk-Jakubowski JL, Shevchenko R, Shevchenko O, Harabin R, Kuchcinski A, Fedorchuk-Moroz V, Khmyrova A, Rushchak I.   +10 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Patient Preferences for the PRIMA Retinal Prosthesis for Vision Restoration for Dry Age-Related Macular Degeneration: An International Survey Study. [PDF]

Transl Vis Sci Technol
Muqit MMK, Villani GM, Dami M, Druchkiv V, Spampinato G, Cadoni S, Hornig R, Holz FG, Bittner AK.   +8 more
europepmc   +1 more source

- Invited Review - Precision livestock farming: from where we came and where we go. [PDF]

Anim Biosci
Berckmans D.
europepmc   +1 more source

The Life and Legacy of Dr. Jonathan Letterman (1824-1872): The Father of Modern Battlefield Medicine. [PDF]

Cureus
Carter J, Meyers N.
europepmc   +1 more source