Results 161 to 170 of about 53,106 (302)

Errors in Figure 2 and Figure 3 [PDF]

open access: yesJAMA Otolaryngology–Head & Neck Surgery, 2018
openaire   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Figurative language impairment in aphasic patients

open access: yes, 2011
Purpose: The present study is a pilot test designed to verify the Figurative Language Battery that we have developed to explore figurative language skills of individuals with aphasia.
Cieślicka, Anna B.   +2 more
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Learning figurative language: the comprehension of taboo metaphors by L2 speakers

open access: yes, 2018
Our paper focuses on the comprehension of figurative language by L2 speakers, with a focus on the comprehension of metaphors that express sexual taboo concepts.
Suner Munoz, Ferran   +2 more
core  

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