Results 101 to 110 of about 17,980,865 (281)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Studia Metrica et Poetica, 2019 This essay discusses the interaction of the divine point of light and Beatrice as the unattainable point of revelation for Dante in Paradiso 30. The two points with their respective circles of understanding and expression form a powerful figure which ...
Ülar Ploom
doaj +1 more source
Exact results for Wilson loops in orbifold ABJM theory
, 2016 We investigate the exact results for circular 1/4 and 1/2 BPS Wilson loops in the $d=3$ ${\mathcal N}=4$ super Chern-Simons-matter theory that could be obtained by orbifolding Aharony-Bergman-Jafferis-Maldacena (ABJM) theory.
Ouyang, Hao, Wu, Jun-Bao, Zhang, Jia-ju
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
L’immaginario e gli oggetti. Per una sociologia della superficie
Im@go. A Journal of the Social Imaginary, 2019 Imaginary and Objects. For a Sociology of Surface. The aim of this paper is to clarify the relationship between objects and imaginary. Objects are investigated as the skin of the imaginary. In this way, objects allow us to define the figure of a specific
Fabio La Rocca, Antonio Tramontana
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Technique for lowering the noise figure in RF amplifiers [PDF]
, 1970 Low-level RF amplifiers are operated at noise figures at or near the theoretical minimum, while maintaining high-gain stability. Formulas for the minimum amplifier noise figure value are derived from the analytical noise-figure expression involving the ...
Bellomo, A. F.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source