Results 101 to 110 of about 185,827 (258)
Safety and pharmacokinetics of inhaled aloxistatin: A first‐in‐human phase 1 dose escalation trial
British Journal of Clinical Pharmacology, EarlyView.Aims Aloxistatin (E64d) is a membrane‐permeable cysteine protease inhibitor prodrug that is converted by esterases to the active metabolite E64c (loxistatin). This first‐in‐human study evaluated the safety, tolerability and pharmacokinetics of single ascending doses of inhaled E64d in healthy volunteers.
Sebastian Fähndrich +24 more
wiley +1 more source
Contagion, Quarantine and Constitutive Rhetoric: Embodiment, Identity and the "Potential Victim" of Infectious Disease. [PDF]
J Med Humanit, 2022 Crowe JH.
europepmc +1 more source
Economic Impact of Collegiate Bass Tournaments: Experiences from Auburn University [PDF]
Recreation and tourism associated with collegiate bass tournaments can play a major role in local economic development as the dollars anglers and tournament organizers spend work their way through the economy.
Swaim, Jenny, Myles, Albert E.
core
Continuous Capture of Recombinant Adeno‐Associated Virus Particles Using Twin‐Column CaptureSMB
Biotechnology and Bioengineering, EarlyView.Continuous twin‐column CaptureSMB enables direct capture of secreted rAAV5 from minimally processed perfusion harvest, bypassing lysis, clarification, and concentration steps. Compared to batch capture, it achieves higher yield (+14.3%), greater productivity (+11.4%), and drastically reduced buffer use (−79.2%), while maintaining critical quality ...
Julia M. Müller +11 more
wiley +1 more source
Organizing the Methodological Toolbox: Lessons Learned From Implementing Developmental Methods Online. [PDF]
Front Psychol, 2021 Kominsky JF +6 more
europepmc +1 more source
Critical Materials Import and Environmental Preferences: Evidence From G20 and N11 Economies
Business Strategy and the Environment, EarlyView.ABSTRACT Critical materials such as lithium and cobalt are indispensable for achieving the United Nations' Sustainable Development Goals (SDGs), particularly SDG 7 (Affordable and Clean Energy) and SDG 13 (Climate Action). While these materials enable the deployment of low‐carbon technologies, including electric vehicle batteries and renewable energy ...
Asif Saeed +2 more
wiley +1 more source
Hepatology, EarlyView., 2022 Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid +20 more
wiley +1 more source
Artificial Intelligence May Predict Early Sepsis After Liver Transplantation. [PDF]
Front Physiol, 2021 Kamaleswaran R +4 more
europepmc +1 more source
Business Strategy and the Environment, EarlyView.ABSTRACT Considering the need for environmental sustainability and fulfillment of the needs of customers at the bottom of the pyramid, this study integrates the attention‐based view of organizations and situational leadership theory to examine the impact of government eco‐initiatives on frugal green innovation through managerial attention toward the ...
Qaisar Iqbal +2 more
wiley +1 more source
Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source