Results 211 to 220 of about 253,182 (298)

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

Advanced Science, EarlyView.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth, Christoph F. Jacob, Alexandra Nguyen, Mandy Beyer, Andreas O. Mieland, Mario Dejung, Jia‐Xuan Chen, Walburgis Brenner, Christina Ehrhardt, Andreas Henke, Oliver H. Krämer   +10 more
wiley   +1 more source

First catheter ablation in Fiji: Innovative use of a pacemaker programmer as a recording system. [PDF]

Heart Rhythm O2
McIlraith B, Jayendrappa A, Cumming T, Youard J, Voss J, Clare G, Webber M, Martin A, Pacific Islands Pacemaker Services.   +8 more
europepmc   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

Patterns of acute watery diarrhea in Fiji: understanding the implications for water and sanitation services. [PDF]

BMC Public Health
Batikawai SM, Osborne NJ, Do P, Vosataki T, Deo V, Reid SA.   +5 more
europepmc   +1 more source

Mitochondrial Enzymes Mimetic Ultrasmall Palladium Nanozymes Prevent Senescence and Neurodegeneration Through Metabolic Reprogramming

Advanced Science, EarlyView.
Simply constructed polyvinylpyrrolidone (PVP) modified palladium nanoparticles (PdP NPs) as cytochrome c oxidase (CcO) and superoxide dismutase (SOD) mimic are promising multifunctional nanoreactors to boost mitochondrial respiration chain function and refine homeostasis via regulation of mitochondrial dynamics and proteostasis sensor UPRmt, which ...
Wenshu Cong, Haiming Jing, Zinan Li, Wenjing Zhang, Nan Zhang, Yingqiu Xie, Shan Gao, Yuanyu Huang, Junyu Ning   +8 more
wiley   +1 more source

Dispersal can spread management benefits: Insights from a modeled Fijian coral reef network. [PDF]

Ecol Appl
Greiner A, Andrello M, Krkošek M, Fortin MJ, Nand Y, Jupiter SD, Mangubhai S, Wenger A, Darling ES.   +8 more
europepmc   +1 more source

Erasable FAP Targeted Spray‐On Probe for Fluorescence‐Guided Surgery

Advanced Science, EarlyView.
We present the first erasable spray‐on probe for fluorescence‐guided surgery. Following topical delivery, FAP‐FLASH550 targets fibroblast activation protein–expressing stromal cells, delineating tumor margins with high tumor‐to‐background ratios. A 365 nm UV light pulse rapidly erases fluorescent signals through triazene photodegradation and subsequent
Zachary Rabinowitz, Riley J. Deutsch‐Williams, Ralph Weissleder   +2 more
wiley   +1 more source

The efficacy of a single dose of oral azithromycin in labour to prevent infections in infants and birthing parents in Fiji: secondary outcomes from a randomised controlled trial. [PDF]

BMJ Glob Health
Hume-Nixon M, Clark S, Ratu T, Nguyen C, Neal EFG, Bright K, Strobel AG, Watts E, Hart J, Fong JJ, Rafai E, Sakumeni K, Steer A, Vereti I, Russell F.   +14 more
europepmc   +1 more source

Bio‐templated Piezoresistive Yarn for High Sensitivity Movement Monitoring Textiles

Advanced Science, EarlyView.
This study developed a conductive coating by biotemplating silver nanoparticles (AgNPs) onto a Potato virus A (PV) particle network, cross‐linked on co‐polyamide‐starch (CoPA‐SS) coils. The combination of CoPA‐SS's shape memory and PV‐AgNP's piezoresistivity achieved high strain sensitivity and minimal hysteresis.
Swarnalok De, Viivi Mäkelä, Matteo Iannacchero, Maija Vaara, Fevzihan Basarir, Hossein Baniasadi, Sharon Saarinen, Jani Sainio, Kristiina Mäkinen, Mauri A. Kostiainen, Jaana Vapaavuori   +10 more
wiley   +1 more source

Ulinastatin attenuates capillary leakage and suppresses FoxO1-dependent angiopoietin-2 in sepsis-associated acute lung injury via PI3K pathway. [PDF]

PLoS One
Lv Y, Meng Y, Rui H, Li T, Zhang J, Liu J, Ma X, Wang J, Yuan Y, Jiang Y, Yan X, Li M, Dong X, Zhang B, Ma L.   +14 more
europepmc   +1 more source