Results 91 to 100 of about 17,224 (237)

Biomarkers for therapeutic response and adverse outcomes in atopic dermatitis: A systematic review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review assessed 52 biomarkers predicting systemic therapy response and adverse events in atopic dermatitis. Most studies focused on dupilumab, and findings were inconsistent. IgE and eosinophils were largely non‐predictive, though elevated eosinophils and LDH sometimes indicated poorer outcomes.
Eva Hilger, Kaitlyn Chan, Alphonsus Yip, Xingyue Maria Wang, Conor Broderick, Bernd Arents, Karin van Bart, Kilian Eyerich, Joseph Rastrick, Stephan Weidinger, Carsten Flohr, on behalf of the BIOMAP Consortium   +11 more
wiley   +1 more source

Salivary cytokine panel indicative of non-small cell lung cancer. [PDF]

, 2018
Objective To develop a combinatorial panel of salivary cytokines that manifests the presence of non-small cell lung cancer (NSCLC) that will eventually improve prognosis by facilitating the early diagnosis and management of this common cancer. Methods We
Koizumi, Tomonobu, Shetty, Vivek, Yamaguchi, Masaki   +2 more
core   +3 more sources

The epidthelial sodium channel ENaC and its regulators in the epidermal permeability barrier function [PDF]

, 2010
The highly amiloride-sensitive epithelial sodium channel ENaC is well known to be involved in controlling whole body sodium homeostasis and lung liquid clearance. ENaC expression has also been detected in the skin of amphibians and mammals.
Charles, R-P., Frateschi, S., Hummler, E.   +2 more
core   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Treatment with Docosahexaenoic Acid Improves Epidermal Keratinocyte Differentiation and Ameliorates Inflammation in Human Keratinocytes and Reconstructed Human Epidermis Models

Molecules, 2019
Atopic dermatitis (AD) is a chronic inflammatory skin disease that can cause skin barrier function damage. Although co-incubation with docosahexaenoic acid (DHA) exerts a positive effect on deficient skin models, no studies have investigated the effects ...
Tinghan Jia, Wu Qiao, Qifeng Yao, Wenhui Wu, Ken Kaku   +4 more
doaj   +1 more source

Evaluation of safety and efficacy of an ophytrium and seboliance‐containing mousse with or without shampoo in cats with keratinisation disorders

Journal of Small Animal Practice, EarlyView.
Objectives This study aimed to assess the effectiveness of a protocol involving the application of topical products (DOUXO® S3 SEB Shampoo and Mousse; Ceva Santé Animale) containing ophytrium for managing feline keratinisation disorders. Materials and Methods Nineteen client‐owned cats with a history of keratinisation disorders exhibited greasy or dry ...
C. Noli, H. Dropsy, A. Cozar, X. De Jaeger, R. Kesteman, A. Beck, R. Cristante, M. Debraine, F. Leymarios, A. Puozzo‐Barichard, M. Gatellet   +10 more
wiley   +1 more source

Recent positive selection in genes of the mammalian epidermal differentiation complex locus [PDF]

, 2017
The epidermal differentiation complex (EDC) is the most rapidly evolving locus in the human genome compared to that of the chimpanzee. Yet the EDC genes that are undergoing positive selection across mammals and in humans are not known.
Goodwin, Zane A, Strong, Cristina de Guzman   +1 more
core   +2 more sources

The State of Prevention of Atopic Dermatitis: An Updated Review

Pediatric Dermatology, EarlyView.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disorder that has a high worldwide prevalence and carries substantial psychosocial and financial burden. As such, the prevention of AD is an important area of research. In this review, we provide an update synthesizing relevant clinical trials published from January 2020 through July 2025 ...
Alexandra Kiszluk, Peter Lio
wiley   +1 more source

Filaggrin mutations and the skin

Indian Journal of Dermatology, Venereology, and Leprology, 2012
Filaggrin is very important in the terminal differentiation of the skin and the formation of cornified envelope in the stratum corneum. Several mutations in the filaggrin gene have been identified in the last decade, mostly from the European countries.
Dipankar, De, Sanjeev, Handa
openaire   +2 more sources

Rheumatoid arthritis specific anti-Sa antibodies target citrullinated vimentin [PDF]

, 2004
Antibodies directed to the Sa antigen are highly specific for rheumatoid arthritis ( RA) and can be detected in approximately 40% of RA sera. The antigen, a doublet of protein bands of about 50 kDa, is present in placenta and in RA synovial tissue ...
Vossenaar, E.R., Despres, N., Lapointe, E., Heijden, A.G. van der, Lora, M., Senshu, T., Venrooij, W.J.W. van, Menard, H.A.   +7 more
core   +1 more source