Results 221 to 230 of about 6,491,911 (254)
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Detection of Several Families of Deiminated Proteins Derived from Filaggrin and Keratins in Guinea Pig Skin

Zoological Science, 1996
Abstract Structural proteins in the mammalian epidermis contain citrulline residues generated by enzymatic deimination of arginine residues. We analyzed deiminated proteins solubilized from sequentially stripped layers of guinea pig epidermis. Deiminated proteins were localized in the granular and cornified layers.
S. Kan, H. Asaga, T. Senshu
semanticscholar   +2 more sources

Assessment of Serum Interleukin-4 and Filaggrin Protein in Patients with Atopic Dermatitis

Medico-Legal Update, 2020
The current study aimed to determine the relationship between certain immunological parameters inatopicdermatitis (AD) patients.There wasno significant differences (P?0.05)in the level offilaggrin protein between patients and controlgroups regarding to the age but there wasa significant differences (P?
openaire   +1 more source

Altered mRNA and protein expression of filaggrin in the skin of a canine animal model for atopic dermatitis

Veterinary Dermatology, 2013
BackgroundFilaggrin is a structural protein that has attracted increasing interest over the past decade for its role in the pathogenesis of human atopic dermatitis (AD). Null mutations in its sequence are considered risk factors in the development of AD.Hypothesis/ObjectivesTo investigate canine filaggrin mRNA and protein expression in the skin of ...
Domenico, Santoro   +4 more
openaire   +2 more sources

Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

Nature Genetics, 2006
Atopic disease, including atopic dermatitis (eczema), allergy and asthma, has increased in frequency in recent decades and now affects approximately 20% of the population in the developed world. Twin and family studies have shown that predisposition to atopic disease is highly heritable.
Palmer, Colin N. A.   +26 more
openaire   +3 more sources

Filaggrin, an Intermediate Filament-Associated Protein: Structural and Functional Implications from the Sequence of a cDNA from Rat

DNA and Cell Biology, 1990
Filaggrin is an intermediate filament-associated protein that is involved in aggregation of keratin filaments in fully cornified cells of the mammalian epidermis, and is an important marker for epidermal differentiation. In this report, the sequence of a rat cDNA clone coding for a portion of the polymeric precursor, profilaggrin, is presented.
P V, Haydock, B A, Dale
openaire   +2 more sources

The characterization of human epidermal filaggrin. A histidine-rich, keratin filament-aggregating protein.

Biochimica et biophysica acta, 1983
Filaggrin is a histidine-rich, cationic protein that aggregates with keratin filaments in vitro and may function as the keratin matrix protein in the terminally differentiated cells of the epidermis. This protein has been previously isolated from rodent epidermis.
A M, Lynley, B A, Dale
openaire   +1 more source

Filaggrin, the matrix protein of keratin

The American Journal of Dermatopathology, 1985
Kurt Stenn, Beverly A. Dale
openaire   +2 more sources

Filaggrin: A Keratin Filament Associated Proteina

Annals of the New York Academy of Sciences, 1985
B A, Dale   +2 more
openaire   +2 more sources

Revisiting the Roles of Filaggrin in Atopic Dermatitis

International Journal of Molecular Sciences, 2022
Verena Moosbrugger-Martinz   +2 more
exaly  

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