Results 31 to 40 of about 2,655 (142)
Background: In patients with essential thrombocythemia (ET) who have high risk factors for thrombotic events, cytoreductive therapy with anagrelide (ANA) or hydroxycarbamide (HC) is one of the treatment options. Despite the clinically evident platelet‐lowering effect of ANA, the detailed mechanism of its effect remains to be elucidated.
N. Miyashita +4 more
wiley +1 more source
Background: Essential thrombocythemia (ET) is a BCR‐ABL1‐negative myeloproliferative neoplasm associated in 50–60% of cases with the presence of the JAK2V617F mutation. Several studies have revealed that oxidative stress induces a growth advantage to JAK2V617F‐ positive clones, but little is known about the antioxidant status of ET patients.
M.‐A. Gaman, C. Moisa, A.M. Gaman
wiley +1 more source
EHA2021 Virtual Congress Abstract Book
HemaSphere, Volume 5, Issue S2, June 2021.
wiley +1 more source
Background: Ponatinib (PON) is a third generation tyrosine kinase inhibitor (TKI) used in adults with chronic myeloid leukaemia (CML) or Ph+ acute lymphoblastic leukaemia who are resistant or intolerant to prior TKIs or those harbouring the BCR‐ABL1T315I mutant.
F.‐E. Nicolini +7 more
wiley +1 more source
Background: In a developing economy like India, Imatinib usage has increased manifold after generic formulations were introduced. 25 brands of generic Imatinib are approved by the Drug Controller General of India. The efficacy and safety of these brands have been repeatedly questioned by different studies.
A. Iqbal +4 more
wiley +1 more source
Background: Chronic myeloid leukaemia (CML) is a chronic myeloproliferative neoplasm associated with a BCR‐ABL1 gene sequence. Some studies have shown that oxidative stress is involved in CML pathogenesis, genomic instability, disease progression and resistance to tyrosine‐kinase inhibitors (TKI).
E.G. Pascu, M.‐A. Gaman, A.M. Gaman
wiley +1 more source
Este artículo aborda las condiciones en las que operan muchas organizaciones no lucrativas dedicadas a los asuntos de mujeres y niñas. Una muestra de entidades localizadas en Haití, Jamaica, Puerto Rico, República Dominicana y Venezuela que, como ...
MARIELY RIVERA-HERNANDEZ
doaj +1 more source
African voices and their role in improving north–south collaborations for biodiversity conservation
Abstract While the dominance of policies from the Global North has shaped conservation practices, holistic decision‐making is urgently needed to incorporate more local voices, especially in Africa. Effective conservation strategies may be enhanced by incorporating the expertise and resources of the Global North alongside the knowledge, lived ...
Kudzai Shaun Mpakairi +10 more
wiley +1 more source
Background: Allogenic stem cells transplantation (Allo‐SCT) is associated with oral mucositis, dysgeusia, nausea, vomiting, diarrhea and abdominal pain that can affect food intake and nutritional status. Parenteral nutrition (PN) can be adopted to contrast these side effects, but no clear data are available concerning the impact of this approach on ...
F. Arena +12 more
wiley +1 more source
Resenha crítica do livro Fundos Patrimoniais Culturais
Resenha crítica da obra Fundos Patrimoniais Culturais, publicada pela Lumen Juris, em 2022, cuja autoria é de Thiago Serpa Erthal. Trata-se de uma discussão sobre os fundos para conservação dos patrimônios culturais brasileiros, regastando conceitos de ...
Nívia Soares da Silva Xaxá +1 more
doaj +1 more source

