Results 31 to 40 of about 2,655 (142)

PF684 ANAGRELIDE MODULATES PROPLATELET FORMATION RESULTING IN DECREASED NUMBER AND INCREASED SIZE OF PLATELETS

open access: yesHemaSphere, Volume 3, Issue S1, Page 296, June 2019., 2019
Background: In patients with essential thrombocythemia (ET) who have high risk factors for thrombotic events, cytoreductive therapy with anagrelide (ANA) or hydroxycarbamide (HC) is one of the treatment options. Despite the clinically evident platelet‐lowering effect of ANA, the detailed mechanism of its effect remains to be elucidated.
N. Miyashita   +4 more
wiley   +1 more source

PF685 THE RELATIONSHIP BETWEEN TOTAL ANTIOXIDANT CAPACITY AND JAK2V617F MUTATION IN ESSENTIAL THROMBOCYTHEMIA

open access: yesHemaSphere, Volume 3, Issue S1, Page 296-297, June 2019., 2019
Background: Essential thrombocythemia (ET) is a BCR‐ABL1‐negative myeloproliferative neoplasm associated in 50–60% of cases with the presence of the JAK2V617F mutation. Several studies have revealed that oxidative stress induces a growth advantage to JAK2V617F‐ positive clones, but little is known about the antioxidant status of ET patients.
M.‐A. Gaman, C. Moisa, A.M. Gaman
wiley   +1 more source

EHA2021 Virtual Congress Abstract Book

open access: yes, 2021
HemaSphere, Volume 5, Issue S2, June 2021.
wiley   +1 more source

PB1923 PONATINIB LONG‐TERM FOLLOW‐UP OF EFFICACY AND SAFETY IN CP‐CML PATIENTS IN REAL WORLD SETTINGS IN FRANCE: THE POST‐PACE STUDY

open access: yesHemaSphere, Volume 3, Issue S1, Page 874-875, June 2019., 2019
Background: Ponatinib (PON) is a third generation tyrosine kinase inhibitor (TKI) used in adults with chronic myeloid leukaemia (CML) or Ph+ acute lymphoblastic leukaemia who are resistant or intolerant to prior TKIs or those harbouring the BCR‐ABL1T315I mutant.
F.‐E. Nicolini   +7 more
wiley   +1 more source

PB1925 COMPARATIVE STUDY OF GLIVEC VERSUS STATE SPONSORED GENERIC IMATINIB MESYLATE AS FIRST LINE THERAPY IN CHRONIC MYELOID LEUKEMIA‐ CHRONIC PHASE

open access: yesHemaSphere, Volume 3, Issue S1, Page 875, June 2019., 2019
Background: In a developing economy like India, Imatinib usage has increased manifold after generic formulations were introduced. 25 brands of generic Imatinib are approved by the Drug Controller General of India. The efficacy and safety of these brands have been repeatedly questioned by different studies.
A. Iqbal   +4 more
wiley   +1 more source

PB1926 THE RELATIONSHIP BETWEEN OXIDATIVE STRESS LEVELS, BCR‐ABL1 TRANSCRIPT VALUES AND TREATMENT WITH TYROSINE KINASE INHIBITORS IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA

open access: yesHemaSphere, Volume 3, Issue S1, Page 875-876, June 2019., 2019
Background: Chronic myeloid leukaemia (CML) is a chronic myeloproliferative neoplasm associated with a BCR‐ABL1 gene sequence. Some studies have shown that oxidative stress is involved in CML pathogenesis, genomic instability, disease progression and resistance to tyrosine‐kinase inhibitors (TKI).
E.G. Pascu, M.‐A. Gaman, A.M. Gaman
wiley   +1 more source

Género, filantropía y Caribe: desafíos operacionales de algunas entidades enfocadas en mujeres que abren camino a otras mujeres

open access: yesRevista de Cultura de Paz, 2022
Este artículo aborda las condiciones en las que operan muchas organizaciones no lucrativas dedicadas a los asuntos de mujeres y niñas. Una muestra de entidades localizadas en Haití, Jamaica, Puerto Rico, República Dominicana y Venezuela que, como ...
MARIELY RIVERA-HERNANDEZ
doaj   +1 more source

African voices and their role in improving north–south collaborations for biodiversity conservation

open access: yesConservation Biology, Volume 39, Issue 4, August 2025.
Abstract While the dominance of policies from the Global North has shaped conservation practices, holistic decision‐making is urgently needed to incorporate more local voices, especially in Africa. Effective conservation strategies may be enhanced by incorporating the expertise and resources of the Global North alongside the knowledge, lived ...
Kudzai Shaun Mpakairi   +10 more
wiley   +1 more source

PB2269 PARENTERAL NUTRITION AND ACUTE GVHD IN HEMATOPOIETIC STEM CELLS TRANSPLANTATION: A PROSPECTIVE OBSERVATIONAL COHORT STUDY

open access: yesHemaSphere, Volume 3, Issue S1, Page 1014-1015, June 2019., 2019
Background: Allogenic stem cells transplantation (Allo‐SCT) is associated with oral mucositis, dysgeusia, nausea, vomiting, diarrhea and abdominal pain that can affect food intake and nutritional status. Parenteral nutrition (PN) can be adopted to contrast these side effects, but no clear data are available concerning the impact of this approach on ...
F. Arena   +12 more
wiley   +1 more source

Resenha crítica do livro Fundos Patrimoniais Culturais

open access: yesPolíticas Culturais em Revista, 2023
Resenha crítica da obra Fundos Patrimoniais Culturais, publicada pela Lumen Juris, em 2022, cuja autoria é de Thiago Serpa Erthal. Trata-se de uma discussão sobre os fundos para conservação dos patrimônios culturais brasileiros, regastando conceitos de ...
Nívia Soares da Silva Xaxá   +1 more
doaj   +1 more source

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