Results 41 to 50 of about 22,662 (214)
Background: In patients with essential thrombocythemia (ET) who have high risk factors for thrombotic events, cytoreductive therapy with anagrelide (ANA) or hydroxycarbamide (HC) is one of the treatment options. Despite the clinically evident platelet‐lowering effect of ANA, the detailed mechanism of its effect remains to be elucidated.
N. Miyashita +4 more
wiley +1 more source
Background: Essential thrombocythemia (ET) is a BCR‐ABL1‐negative myeloproliferative neoplasm associated in 50–60% of cases with the presence of the JAK2V617F mutation. Several studies have revealed that oxidative stress induces a growth advantage to JAK2V617F‐ positive clones, but little is known about the antioxidant status of ET patients.
M.‐A. Gaman, C. Moisa, A.M. Gaman
wiley +1 more source
EHA2021 Virtual Congress Abstract Book
HemaSphere, Volume 5, Issue S2, June 2021.
wiley +1 more source
Background: Ponatinib (PON) is a third generation tyrosine kinase inhibitor (TKI) used in adults with chronic myeloid leukaemia (CML) or Ph+ acute lymphoblastic leukaemia who are resistant or intolerant to prior TKIs or those harbouring the BCR‐ABL1T315I mutant.
F.‐E. Nicolini +7 more
wiley +1 more source
“Filantropia” or “Non Profit”? Translating Texts on Nonprofits from English into Italian [PDF]
This paper describes the problems that arise in the translation of texts on – and by – the nonprofit sector from English (especially American English) into Italian.
Fusari, Sabrina
core +1 more source
OS EQUÍVOCOS LEGAIS DA FILANTROPIA
Este artigo procura evidenciar as dificuldades que as entidades filantrópicas enfrentam de desenvolverem suas ações nas áreas da educação e da saúde em função das dificuldades, cada vez maiores, de enquadramento na legislação pertinente. Permanecendo o quadro atual, com as isenções menores do que os encargos de assistência social, muitas entidades ...
Wanderlei José Ghilardi +1 more
openaire +2 more sources
Background: In a developing economy like India, Imatinib usage has increased manifold after generic formulations were introduced. 25 brands of generic Imatinib are approved by the Drug Controller General of India. The efficacy and safety of these brands have been repeatedly questioned by different studies.
A. Iqbal +4 more
wiley +1 more source
CHALLENGES IN THE DIAGNOSIS OF PEDIATRIC PNEUMONIA [PDF]
Pneumonia is a form of acute respiratory infection that affects the lungs and it is the leading cause of illness and death in children worldwide. Pneumonia can occur at any age, but it is more common in younger children.
Ligia Georgeta Stanescu +7 more
doaj +1 more source
Background: Chronic myeloid leukaemia (CML) is a chronic myeloproliferative neoplasm associated with a BCR‐ABL1 gene sequence. Some studies have shown that oxidative stress is involved in CML pathogenesis, genomic instability, disease progression and resistance to tyrosine‐kinase inhibitors (TKI).
E.G. Pascu, M.‐A. Gaman, A.M. Gaman
wiley +1 more source
Principales tendencias de la filantropia en America Latina [PDF]
Durante las últimas décadas se conformó una nueva filantropía más organizada, integrada por fundaciones privadas y corporativas, instituciones de cooperación internacional, entidades religiosas y principalmente organizaciones con fines sociales que han ...
core

