Results 31 to 40 of about 59,491 (300)

Dosing pole recommendations for lymphatic filariasis elimination: A height-weight quantile regression modeling approach [PDF]

open access: yes, 2019
BACKGROUND: The World Health Organization (WHO) currently recommends height or age-based dosing as alternatives to weight-based dosing for mass drug administration lymphatic filariasis (LF) elimination programs.
Dubray, Christine   +14 more
core   +2 more sources

Prevalence and intensity of human soil transmitted helminth infections in the Akonolinga health district (Centre Region, Cameroon): Are adult hosts contributing in the persistence of the transmission?

open access: yesParasite Epidemiology and Control, 2016
Background: Soil-transmitted helminthiases (STHs) are among the most prevalent afflictions of the developing world, with approximately 2 billion people infected worldwide. Heavily infected individuals suffer from severe morbidity that can result in death.
Jean Bopda   +6 more
doaj   +1 more source

Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis

open access: yesScience Translational Medicine, 2019
An oral macrolide drug targeting the bacterial endosymbiont, Wolbachia, shows efficacy against filarial nematodes in preclinical animal models. Nematodes go A·WOL New drugs are urgently needed for treating the neglected tropical diseases, onchocerciasis ...
M. Taylor   +31 more
semanticscholar   +1 more source

Genital manifestations of tropical diseases [PDF]

open access: yes, 2004
Genital symptoms in tropical countries and among returned travellers can arise from a variety of bacterial, protozoal, and helminthic infections which are not usually sexually transmitted.
Richens, J
core   +2 more sources

AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Onchocerciasis (river blindness) and lymphatic filariasis (elephantiasis) are neglected tropical diseases that cause severe disability and affect more than 157 million people globally.
W. Hong   +33 more
semanticscholar   +1 more source

Lymphatic Filariasis Control in Tanzania: Effect of Six Rounds of Mass Drug Administration with Ivermectin and Albendazole on Infection and Transmission. [PDF]

open access: yes, 2013
Control of lymphatic filariasis (LF) in most countries of sub-Saharan Africa is based on annual mass drug administration (MDA) with a combination of ivermectin and albendazole, in order to interrupt transmission. We present findings from a detailed study
C Chaccour   +48 more
core   +1 more source

A Randomized Trial of a New Triple Drug Treatment for Lymphatic Filariasis

open access: yesNew England Journal of Medicine, 2018
BACKGROUND The World Health Organization has targeted lymphatic filariasis for global elimination by 2020 with a strategy of mass drug administration. This trial tested whether a single dose of a three‐drug regimen of ivermectin plus diethylcarbamazine ...
C. King   +9 more
semanticscholar   +1 more source

Development of Conventional Multiplex PCR: A Rapid Technique for Simultaneous Detection of Soil-Transmitted Helminths

open access: yesPathogens, 2019
Soil-transmitted helminths (STHs) are the most common intestinal parasites infecting humans worldwide. STH infections are a major cause of morbidity and disability.
Vivornpun Sanprasert   +5 more
doaj   +1 more source

Risk Factor Analysis of Filariasis in Pidie Regency

open access: yesJurnal Kesehatan Lingkungan, 2023
Introduction: Pidie Regency is a regency in Aceh Province with the second-highest number of filariasis patients in 2020. One of the risk factors for filariasis is the presence of stagnant water near houses which serves as the breeding ground and resting ...
Maifrizal Maifrizal   +2 more
doaj   +1 more source

Clinical Relevance of Animal Models of Lymphatic Dysfunction and Lymphedema. [PDF]

open access: yesMicrocirculation
ABSTRACT Lymphedema is a chronic progressive condition, and treatment options are limited to physical therapy or surgical intervention, underscoring the need to develop preventative strategies. To do so, we must first understand the underlying mechanisms that contribute to the development of clinical lymphedema, which can be caused by a myriad of ...
Podder PS   +4 more
europepmc   +2 more sources

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