Results 91 to 100 of about 284,225 (286)

Gromacs MetaDump: a tool for extracting GROMACS simulation metadata

open access: yesJournal of Cheminformatics
The volume of molecular dynamics (MD) simulation data shared via public repositories is rapidly increasing; however, fragmentation across multiple independent repositories, each employing distinct dataset identifiers and metadata schemas, hinders the ...
Adrián Rošinec   +11 more
doaj   +1 more source

Analysis of methods for removing the fragments of instruments from the root canal system

open access: yesЭндодонтия Today
INTRODUCTION. Endodontics is a constantly developing area of dentistry. Every year new systems of machine rotating nickel-titanium instruments appear on the dental market which is accompanied by an increase in the incidence of such a complication of ...
A. V. Mitronin   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The Proton Spin Puzzle and $\Lambda$ Polarization in Deep--Inelastic Scattering

open access: yes, 1995
We point out that measurements of longitudinal $\Lambda$ polarization in the target fragmentation region of deep--inelastic $\nu \,N$ and $\mu \,N$ or $e \, N$ scattering may test dynamical mechanisms invoked to explain the proton spin puzzle.
Ellis, John   +2 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

A Majority of Family Physicians Use a Hospitalist Service When Their Patients Require Inpatient Care

open access: yesJournal of Primary Care & Community Health, 2015
Background: The hospitalist movement in the United States has risen in prominence over the past 2 decades with more physicians practicing as hospitalists.
Douglas Ivins   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Heated nuclear matter, condensation phenomena and the hadronic equation of state

open access: yes, 1995
The thermodynamic properties of heated nuclear matter are explored using an exactly solvable canonical ensemble model. This model reduces to the results of an ideal Fermi gas at low temperatures.
A. J. Cole   +34 more
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

The formation of close binary systems

open access: yes, 1994
A viable solution to the origin of close binary systems, unaccounted for in recent theories, is presented. Fragmentation, occurring at the end of the secondary collapse phase (during which molecular hydrogen is dissociating), can form binary systems with
Bate, Matthew R., Bonnell, Ian A.
core   +1 more source

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