PepLess: A computational tool developed to optimize SPOT synthesis and analyze related immunoassay data. [PDF]
Medina-Santos R +8 more
europepmc +1 more source
Multi‐Material Additive Manufacturing of Soft Robotic Systems: A Comprehensive Review
This review explores the transformative role of multi‐material additive manufacturing (MMAM) in the development of soft robotic systems. It presents current techniques, materials, and design strategies that enable functionally graded and adaptive structures.
Ritik Raj +2 more
wiley +1 more source
MS<sup>n</sup>Lib: efficient generation of open multi-stage fragmentation mass spectral libraries. [PDF]
Brungs C +12 more
europepmc +1 more source
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan +10 more
wiley +1 more source
Normalized compression distance for DNA classification. [PDF]
Hearne G +4 more
europepmc +1 more source
This study identifies TRIM47 as a key driver of liver cancer progression by promoting glycolysis through ubiquitin‐mediated degradation of the gluconeogenic enzyme FBP1. TRIM47 enhances glucose uptake, lactate and ATP production, and tumor growth and metastasis.
Weijie Sun +17 more
wiley +1 more source
Spatial genetic diversity and populational differentiation of Ternstroemia sylvatica (Ericales: Pentaphylacaceae) in eastern Mexico. [PDF]
Alvarado-Sizzo H +4 more
europepmc +1 more source
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
Design and Analysis of Untargeted Metabolomics Experiments. [PDF]
Long ZG, Martin RW.
europepmc +1 more source
DRD2 Deficiency Underlies Pituitary Adenoma Dependent on Escherichia coli Translocation from the Gut
Dopamine receptor D2 (DRD2) deficiency disrupts epithelial barrier integrity in both the gut and pituitary gland, facilitating translocation of gut‐derived Escherichia coli into pituitary tissue. Intratumoral E. coli are phagocytosed by microglia, triggering GSDMD‐dependent pyroptosis and HMGB1 release, which subsequently activates MAPK signaling to ...
Xian‐jun Su +16 more
wiley +1 more source

