Results 111 to 120 of about 533,194 (286)

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi   +5 more
wiley   +1 more source

Fundamental Limits of Caching with Secure Delivery

open access: yes
Caching is emerging as a vital tool for alleviating the severe capacity crunch in modern content-centric wireless networks. The main idea behind caching is to store parts of popular content in end-users' memory and leverage the locally stored content to ...
Clancy, T. Charles   +2 more
core   +2 more sources

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Preventing lipophilic aggregation in cosolvent molecular dynamics simulations with hydrophobic probes using Plumed Automatic Restraining Tool (PART)

open access: yesJournal of Cheminformatics
Cosolvent molecular dynamics (MD) simulations are molecular dynamics simulations used to identify preferable locations of small organic fragments on a protein target.
Olivier Beyens, Hans De Winter
doaj   +1 more source

Influence of Thermal Pretreatments on the Cyclic Fatigue Resistance of Novel Reciprocating Nickel-Titanium Files: A Comparison of Low- and High-Temperature Modified Systems

open access: yesEuropean Endodontic Journal
Introduction: The flexibility and fracture resistance of nickel-titanium (NiTi) files have revolutionised root canal preparation—but file fractures caused by cyclic fatigue or torsional failure are challenging.
Christoph Matthias Schoppmeier   +4 more
doaj   +1 more source

On relating CTL to Datalog

open access: yes
CTL is the dominant temporal specification language in practice mainly due to the fact that it admits model checking in linear time. Logic programming and the database query language Datalog are often used as an implementation platform for logic ...
Afrati, Foto   +4 more
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Optimizing MDS Codes for Caching at the Edge

open access: yes
In this paper we investigate the problem of optimal MDS-encoded cache placement at the wireless edge to minimize the backhaul rate in heterogeneous networks.
Bioglio, Valerio   +2 more
core   +2 more sources

Mycophenolate Mofetil Treatment Reduces the Risk of Treatment Escalation Due to Vascular Complications in Limited Cutaneous Systemic Sclerosis: Emulation of a Target Trial From the Italian Rheumatology Society SPRING Registry

open access: yesArthritis Care &Research, EarlyView.
Objective Mycophenolate mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon because of the lower fibrotic burden and the predominance of vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis   +77 more
wiley   +1 more source

Optimal Deterministic Polynomial-Time Data Exchange for Omniscience

open access: yes
We study the problem of constructing a deterministic polynomial time algorithm that achieves omniscience, in a rate-optimal manner, among a set of users that are interested in a common file but each has only partial knowledge about it as side-information.
Gastpar, Michael   +4 more
core   +1 more source

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